Literature DB >> 6331930

Interleukin-2 activated peripheral blood lymphocytes and the correlation of lytic activity and peanut agglutinin receptor expression on malignant cells.

Y I Gotoh, M Minegishi, Y Yamaguchi, T Konno, K Tada.   

Abstract

The possibility that the peanut agglutinin (PNA) receptor and/or its co-ordinate structures on the surface of leukaemia cells might be recognized by lectin free crude interleukin-2 (IL-2) activated human peripheral blood lymphocytes (LAK) was investigated. Analysis was undertaken of the correlation between the sensitivity to allogeneic LAK lysis and the proportion of PNA receptor on different fresh malignant cells. The results obtained suggested that PNA receptor detected by rhodamine isothiocyanate labelled PNA binding assay appeared to be well expressed on leukaemia cells which were sensitive targets for LAK. PNA receptor and/or its coordinate structures seemed to provide a 'target' structure for LAK.

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Year:  1984        PMID： 6331930      PMCID： PMC1536272     

Source DB:  PubMed          Journal:  Clin Exp Immunol        ISSN： 0009-9104            Impact factor:   4.330


  8 in total

1.  In vitro immunization to cultured human tumor cells.

Authors:  B Sharma; P I Terasaki
Journal:  Cancer Res       Date:  1974-01       Impact factor: 12.701

2.  The purification and properties of human T cell growth factor.

Authors:  J W Mier; R C Gallo
Journal:  J Immunol       Date:  1982-03       Impact factor: 5.422

3.  Lectin-like activities associated with human and murine neoplastic cells.

Authors:  A Raz; R Lotan
Journal:  Cancer Res       Date:  1981-09       Impact factor: 12.701

4.  Monoclonal antibodies which distinguish between human NK cells and cytotoxic T lymphocytes.

Authors:  J M Zarling; P C Kung
Journal:  Nature       Date:  1980-11-27       Impact factor: 49.962

5.  Removal of PHA from supernatants containing T-cell growth factor.

Authors:  J Alvarez; J Rodríguez; M López-Botet; A Silva; M O De Landazuri
Journal:  J Immunol Methods       Date:  1981       Impact factor: 2.303

6.  T cell growth factor from human splenic cell cultures: conditions for its production, and its utilization for maintenance of cytotoxic T cell lines.

Authors:  Y Tanaka; K Sugamura; Y Hinuma
Journal:  Microbiol Immunol       Date:  1981       Impact factor: 1.955

7.  Lymphokine-activated killer cell phenomenon. II. Precursor phenotype is serologically distinct from peripheral T lymphocytes, memory cytotoxic thymus-derived lymphocytes, and natural killer cells.

Authors:  E A Grimm; K M Ramsey; A Mazumder; D J Wilson; J Y Djeu; S A Rosenberg
Journal:  J Exp Med       Date:  1983-03-01       Impact factor: 14.307

8.  Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes.

Authors:  E A Grimm; A Mazumder; H Z Zhang; S A Rosenberg
Journal:  J Exp Med       Date:  1982-06-01       Impact factor: 14.307
  8 in total

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