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Literature DB >> 6331845

Senile atrophy of the human lacrimal gland: the contribution of chronic inflammatory disease.

B E Damato, D Allan, S B Murray, W R Lee.

Abstract

Histological examination of 99 human lacrimal glands showed a relationship between atrophy of the secretory acini and secretory duct obstruction, ascending periductal fibrosis, and obliteration of the adjacent blood vessels caused by lymphocytic and polymorphonuclear inflammation. Investigation of the subgroups of the B lymphocytic series by immunohistochemistry did not show any statistical change with age, sex, fibrosis, or lymphocytic inflammation. The concept of senile atrophy occurring as a result of senescent involution of the lacrimal gland is challenged on the basis of the histological findings.

Entities: Disease Species

Mesh：

Year: 1984 PMID： 6331845 PMCID： PMC1040437 DOI： 10.1136/bjo.68.9.674

Source DB: PubMed Journal: Br J Ophthalmol ISSN： 0007-1161 Impact factor: 4.638

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