Literature DB >> 6331487

Levels of arachidonic acid and its metabolites in the skin in human allergic and irritant contact dermatitis.

R M Barr, S Brain, R D Camp, J Cilliers, M W Greaves, A I Mallet, K Misch.   

Abstract

Increased concentrations of arachidonic acid and prostaglandin E2, but not 12-hydroxy-eicosatetraenoic acid, were found in the skin in human contact dermatitis due to nickel and chromate allergens. Significant levels of neutrophil chemokinetic activity, with similar properties to leukotriene B4, were found in a high proportion of exudates from inflamed skin treated with allergen but not in exudates from untreated skin. Neither arachidonic acid nor its metabolites were increased in primary irritant dermatitis due to benzylalkonium chloride.

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Year:  1984        PMID： 6331487     DOI： 10.1111/j.1365-2133.1984.tb04012.x

Source DB:  PubMed          Journal:  Br J Dermatol        ISSN： 0007-0963            Impact factor:   9.302


  13 in total

1.  The release of leukotriene B4 from human skin in response to substance P: evidence for the functional heterogeneity of human skin mast cells among individuals.

Authors:  T Okabe; M Hide; O Koro; N Nimi; S Yamamoto
Journal:  Clin Exp Immunol       Date:  2001-04       Impact factor: 4.330

Review 2.  [Contact dermatitis. II].

Authors:  P J Frosch; T Rustemeyer; A Schnuch
Journal:  Hautarzt       Date:  1996-12       Impact factor: 0.751

Review 3.  Leukotrienes in inflammation.

Authors:  M A Bray
Journal:  Agents Actions       Date:  1986-10

4.  Effect of a 5-lipoxygenase inhibitor, ZM 230487, on cutaneous allergic inflammation in the guinea-pig.

Authors:  M M Teixeira; P G Hellewell
Journal:  Br J Pharmacol       Date:  1994-04       Impact factor: 8.739

5.  Topical steroid treatment reduces arachidonic acid and leukotriene B4 in lesional skin of psoriasis.

Authors:  E Wong; R M Barr; F M Cunningham; K Mistry; P M Woollard; A I Mallet; M W Greaves
Journal:  Br J Clin Pharmacol       Date:  1986-12       Impact factor: 4.335

6.  Activation of the human neutrophil 5-lipoxygenase by leukotriene B4.

Authors:  P P McDonald; S R McColl; P H Naccache; P Borgeat
Journal:  Br J Pharmacol       Date:  1992-09       Impact factor: 8.739

7.  Leukotriene B4-induced granulocyte trafficking in guinea pig dermis. Effect of second-generation leukotriene B4 receptor antagonists, SC-50605 and SC-51146.

Authors:  D J Fretland; D L Widomski; C P Anglin; T D Penning; S Yu; S W Djuric
Journal:  Inflammation       Date:  1993-06       Impact factor: 4.092

8.  Antiinflammatory effects of second-generation leukotriene B4 receptor antagonist, SC-53228: impact upon leukotriene B4- and 12(R)-HETE-mediated events.

Authors:  D J Fretland; C P Anglin; M Bremer; P Isakson; D L Widomski; S K Paulson; S H Docter; S W Djuric; T D Penning; S Yu
Journal:  Inflammation       Date:  1995-04       Impact factor: 4.092

9.  Lipoxygenase products of arachidonic acid in human inflamed skin.

Authors:  A K Black; R M Barr; E Wong; S Brain; M W Greaves; R Dickinson; B Shroot; C N Hensby
Journal:  Br J Clin Pharmacol       Date:  1985-09       Impact factor: 4.335

10.  The sunburn response in human skin is characterized by sequential eicosanoid profiles that may mediate its early and late phases.

Authors:  Lesley E Rhodes; Karl Gledhill; Mojgan Masoodi; Ann K Haylett; Margaret Brownrigg; Anthony J Thody; Desmond J Tobin; Anna Nicolaou
Journal:  FASEB J       Date:  2009-07-07       Impact factor: 5.191
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