Literature DB >> 6330910

The effect of interferon on flaviviruses in vitro: a preliminary study.

S Vithanomsat, C Wasi, C Harinasuta, P Thongcharoen.   

Abstract

The preliminary results of our study in vitro on the effect of Interferon on Flaviviruses showed that Interferon alpha and Interferon beta were more effective on JE viruses Vip local strain and JaGAr strain, but less on Dengue virus type 2 strain. However, the effect of these 2 interferons on the 2 strains of JE viruses were still variable which need further investigations. The JE virus Vip local strain seemed to be more susceptible to interferon than the Japanese prototype JaGAr strain. Thus, the in vivo trial on JE disease in Thailand is strongly recommended.

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Year:  1984        PMID: 6330910

Source DB:  PubMed          Journal:  Southeast Asian J Trop Med Public Health        ISSN: 0125-1562            Impact factor:   0.267


  5 in total

1.  Randomized, placebo-controlled trial of nonpegylated and pegylated forms of recombinant human alpha interferon 2a for suppression of dengue virus viremia in rhesus monkeys.

Authors:  C Ajariyakhajorn; M P Mammen; T P Endy; M Gettayacamin; A Nisalak; S Nimmannitya; D H Libraty
Journal:  Antimicrob Agents Chemother       Date:  2005-11       Impact factor: 5.191

2.  Modulation of Dengue virus infection in human cells by alpha, beta, and gamma interferons.

Authors:  M S Diamond; T G Roberts; D Edgil; B Lu; J Ernst; E Harris
Journal:  J Virol       Date:  2000-06       Impact factor: 5.103

3.  Delayed cytosolic exposure of Japanese encephalitis virus double-stranded RNA impedes interferon activation and enhances viral dissemination in porcine cells.

Authors:  Lyre Anni Espada-Murao; Kouichi Morita
Journal:  J Virol       Date:  2011-04-27       Impact factor: 5.103

4.  Blocking of the alpha interferon-induced Jak-Stat signaling pathway by Japanese encephalitis virus infection.

Authors:  Ren-Jye Lin; Ching-Len Liao; Elong Lin; Yi-Ling Lin
Journal:  J Virol       Date:  2004-09       Impact factor: 5.103

5.  Dengue and soluble mediators of the innate immune system.

Authors:  Lyre Anni Espada-Murao; Kouichi Morita
Journal:  Trop Med Health       Date:  2011-09-13
  5 in total

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