Literature DB >> 6330561

Complete primary structure of a heterodimeric T-cell receptor deduced from cDNA sequences.

H Saito, D M Kranz, Y Takagaki, A C Hayday, H N Eisen, S Tonegawa.   

Abstract

Two related, but distinct, cDNA clones have been isolated and sequenced from a functional murine cytotoxic T-lymphocyte clone. The genes corresponding to these cDNA are expressed and rearranged specifically in T cells and both have similarities to immunoglobulin variable and constant region genes. It is concluded that these genes code for the two subunits of the heterodimeric antigen receptor on the surface of the T cell; its complete deduced primary structure is presented.

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Year:  1984        PMID: 6330561     DOI: 10.1038/309757a0

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  186 in total

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3.  Casting new light on the TCR.

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4.  Evolutionary conservation of antigen recognition: the chicken T-cell receptor beta chain.

Authors:  L W Tjoelker; L M Carlson; K Lee; J Lahti; W T McCormack; J M Leiden; C L Chen; M D Cooper; C B Thompson
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5.  Self heat shock and gamma delta T-cell reactivity.

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Journal:  Proc Natl Acad Sci U S A       Date:  1990-03       Impact factor: 11.205

6.  Close linkage of the mouse and human CD3 gamma- and delta-chain genes suggests that their transcription is controlled by common regulatory elements.

Authors:  H Saito; T Koyama; K Georgopoulos; H Clevers; W G Haser; T LeBien; S Tonegawa; C Terhorst
Journal:  Proc Natl Acad Sci U S A       Date:  1987-12       Impact factor: 11.205

7.  Amino acids bracketing the predicted transmembrane domains of membrane proteins.

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Journal:  Pharm Res       Date:  1989-09       Impact factor: 4.200

8.  Sequence and diversity of bovine T-cell receptor beta-chain genes.

Authors:  A Tanaka; N Ishiguro; M Shinagawa
Journal:  Immunogenetics       Date:  1990       Impact factor: 2.846

9.  AKR murine thymic leukemias are from a distinct thymic cell lineage and do not express the beta chain of the T-cell antigen receptor.

Authors:  F L Owen; W M Strauss; C Murre; A D Duby; H Hiai; J G Seidman
Journal:  Proc Natl Acad Sci U S A       Date:  1986-10       Impact factor: 11.205

Review 10.  A cold-blooded view of adaptive immunity.

Authors:  Martin F Flajnik
Journal:  Nat Rev Immunol       Date:  2018-07       Impact factor: 53.106

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