Literature DB >> 6330043

Isolation and analysis of inhibitors of transposon Tn3 site-specific recombination.

M A Fennewald, J Capobianco.   

Abstract

We have constructed a genetic bioassay for inhibitors of site-specific recombination by transposon Tn3 resolvase. Of 6,000 compounds tested, 26 inhibited in vivo, and 5 of these 26 inhibited in vitro. At least two inhibitors also inhibit the topoisomerase of resolvase. We have also identified analogs of A1062 which inhibit.

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Year:  1984        PMID： 6330043      PMCID： PMC215648          DOI： 10.1128/jb.159.1.404-406.1984

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  8 in total

1.  Analysis of sequences transposed by complementation of two classes of transposition-deficient mutants of Tn3.

Authors:  R Gill; F Heffron; G Dougan; S Falkow
Journal:  J Bacteriol       Date:  1978-11       Impact factor: 3.490

2.  Transposition protein of Tn3: identification and characterisation of an essential repressor-controlled gene product.

Authors:  J Chou; P G Lemaux; M J Casadaban; S N Cohen
Journal:  Nature       Date:  1979 Dec 20-27       Impact factor: 49.962

3.  Resolution of cointegrates between transposons gamma delta and Tn3 defines the recombination site.

Authors:  R R Reed
Journal:  Proc Natl Acad Sci U S A       Date:  1981-06       Impact factor: 11.205

4.  Transposon-mediated site-specific recombination: a defined in vitro system.

Authors:  R R Reed
Journal:  Cell       Date:  1981-09       Impact factor: 41.582

5.  p lambda CM system: observations on the roles of transposable elements in formation and breakdown of plasmids derived from bacteriophage lambda replicons.

Authors:  C J Muster; L A MacHattie; J A Shapiro
Journal:  J Bacteriol       Date:  1983-02       Impact factor: 3.490

6.  Site-specific relaxation and recombination by the Tn3 resolvase: recognition of the DNA path between oriented res sites.

Authors:  M A Krasnow; N R Cozzarelli
Journal:  Cell       Date:  1983-04       Impact factor: 41.582

7.  Deletions affecting the transposition of an antibiotic resistance gene.

Authors:  F Heffron; P Bedinger; J J Champoux; S Falkow
Journal:  Proc Natl Acad Sci U S A       Date:  1977-02       Impact factor: 11.205

8.  Transposon Tn3 encodes a site-specific recombination system: identification of essential sequences, genes, and actual site of recombination.

Authors:  R Kostriken; C Morita; F Heffron
Journal:  Proc Natl Acad Sci U S A       Date:  1981-07       Impact factor: 11.205
  8 in total
  2 in total

Review 1.  Ecology and evolution as targets: the need for novel eco-evo drugs and strategies to fight antibiotic resistance.

Authors:  Fernando Baquero; Teresa M Coque; Fernando de la Cruz
Journal:  Antimicrob Agents Chemother       Date:  2011-05-16       Impact factor: 5.191

Review 2.  Targeting Plasmids to Limit Acquisition and Transmission of Antimicrobial Resistance.

Authors:  Corneliu Ovidiu Vrancianu; Laura Ioana Popa; Coralia Bleotu; Mariana Carmen Chifiriuc
Journal:  Front Microbiol       Date:  2020-05-06       Impact factor: 5.640
  2 in total

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