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Literature DB >> 6330040

Regulation of a macrolide resistance-beta-galactosidase (ermC-lacZ) gene fusion in Escherichia coli.

Abstract

A fusion constructed between the putative attenuator plus the first 219 nucleotides of the ermC (erythromycin resistance) structural gene and a 5' terminally deleted lacZ gene produced a moderate, basal level of beta-galactosidase which was increased by erythromycin addition. Another construction containing an intact ermC gene in addition to the fusion produced lower levels of beta-galactosidase, suggesting that the ermC gene product exerts negative feedback control on expression.

Entities: Chemical Species

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Year: 1984 PMID： 6330040 PMCID： PMC215641 DOI： 10.1128/jb.159.1.381-384.1984

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

15 in total

1. Three distinct plasmids originating in the same Staphylococcus aureus strain.

Authors: S Iordănescu
Journal: Arch Roum Pathol Exp Microbiol Date: 1976 Jan-Jun

2. Biological studies with rosamicin, a new Micromonospora-produced macrolide antibiotic.

Authors: J A Waitz; C G Drube; E L Moss; M J Weinstein
Journal: J Antibiot (Tokyo) Date: 1972-11 Impact factor: 2.649

3. Conformational alteration of mRNA structure and the posttranscriptional regulation of erythromycin-induced drug resistance.

Authors: T J Gryczan; G Grandi; J Hahn; R Grandi; D Dubnau
Journal: Nucleic Acids Res Date: 1980-12-20 Impact factor: 16.971

4. In vitro gene fusions that join an enzymatically active beta-galactosidase segment to amino-terminal fragments of exogenous proteins: Escherichia coli plasmid vectors for the detection and cloning of translational initiation signals.

Authors: M J Casadaban; J Chou; S N Cohen
Journal: J Bacteriol Date: 1980-08 Impact factor: 3.490

5. Plasmid copy number control: isolation and characterization of high-copy-number mutants of plasmid pE194.

Authors: B Weisblum; M Y Graham; T Gryczan; D Dubnau
Journal: J Bacteriol Date: 1979-01 Impact factor: 3.490

6. Construction and characterization of new cloning vehicles. II. A multipurpose cloning system.

Authors: F Bolivar; R L Rodriguez; P J Greene; M C Betlach; H L Heyneker; H W Boyer; J H Crosa; S Falkow
Journal: Gene Date: 1977 Impact factor: 3.688

7. Characterization of a plasmid-specified ribosome methylase associated with macrolide resistance.

Authors: A G Shivakumar; D Dubnau
Journal: Nucleic Acids Res Date: 1981-06-11 Impact factor: 16.971

8. Posttranscriptional regulation of an erythromycin resistance protein specified by plasmic pE194.

Authors: A G Shivakumar; J Hahn; G Grandi; Y Kozlov; D Dubnau
Journal: Proc Natl Acad Sci U S A Date: 1980-07 Impact factor: 11.205

9. Posttranscriptional modification of mRNA conformation: mechanism that regulates erythromycin-induced resistance.

Authors: S Horinouchi; B Weisblum
Journal: Proc Natl Acad Sci U S A Date: 1980-12 Impact factor: 11.205

10. The 3'-terminal sequence of Escherichia coli 16S ribosomal RNA: complementarity to nonsense triplets and ribosome binding sites.

Authors: J Shine; L Dalgarno
Journal: Proc Natl Acad Sci U S A Date: 1974-04 Impact factor: 11.205

7 in total

1. Picky nascent peptides do not talk to foreign ribosomes.

Authors: Nora Vázquez-Laslop; Alexander S Mankin
Journal: Proc Natl Acad Sci U S A Date: 2011-04-04 Impact factor: 11.205

2. Translational autoregulation of ermC 23S rRNA methyltransferase expression in Bacillus subtilis.

Authors: C D Denoya; D H Bechhofer; D Dubnau
Journal: J Bacteriol Date: 1986-12 Impact factor: 3.490

3. Mechanism of erythromycin-induced ermC mRNA stability in Bacillus subtilis.

Authors: D H Bechhofer; K H Zen
Journal: J Bacteriol Date: 1989-11 Impact factor: 3.490

4. Construction and application of a promoter-probe plasmid that allows chromogenic identification in Streptomyces lividans.

Authors: S Horinouchi; T Beppu
Journal: J Bacteriol Date: 1985-04 Impact factor: 3.490