Literature DB >> 6329453

Identification of an amiloride sensitive Na+/H+ exchange system in brain synaptosomes.

S Sauvaigo, P Vigne, C Frelin, M Lazdunski.   

Abstract

This paper reports the presence of a Na+-uptake component in rat brain synaptosomes that is coupled to H+-efflux as monitored from the acidification of the extrasynaptosomal space. This exchange mechanism is inhibited by amiloride and two of its more potent derivatives: dimethylamiloride and ethylisopropylamiloride.

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Year:  1984        PMID： 6329453     DOI： 10.1016/0006-8993(84)91106-5

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  9 in total

1.  Anionic selectivity sequence of the Cl(-)-H+ symporter in the synaptosomal preparation from rat brain cortex.

Authors:  M L Torres; F Ortega; I Cuaranta; J González; S Sanchez-Armass
Journal:  Neurochem Res       Date:  2008-04-11       Impact factor: 3.996

2.  Na(+)/H(+) exchanger inhibition modifies dopamine neurotransmission during normal and metabolic stress conditions.

Authors:  Marcelo A Rocha; David P Crockett; Lai-Yoong Wong; Jason R Richardson; Patricia K Sonsalla
Journal:  J Neurochem       Date:  2008-07-01       Impact factor: 5.372

3.  Influence of isolation media on synaptosomal properties: intracellular pH, pCa, and Ca2+ uptake.

Authors:  C Bandeira-Duarte; C A Carvalho; E J Cragoe Júnior; A P Carvalho
Journal:  Neurochem Res       Date:  1990-03       Impact factor: 3.996

4.  Interactions of bilirubin with isolated presynaptic nerve terminals: functional effects on the uptake and release of neurotransmitters.

Authors:  E L Ochoa; R P Wennberg; Y An; T Tandon; T Takashima; T Nguyen; A Chui
Journal:  Cell Mol Neurobiol       Date:  1993-02       Impact factor: 5.046

5.  Regulation of dendritic spine growth through activity-dependent recruitment of the brain-enriched Na⁺/H⁺ exchanger NHE5.

Authors:  Graham H Diering; Fergil Mills; Shernaz X Bamji; Masayuki Numata
Journal:  Mol Biol Cell       Date:  2011-05-05       Impact factor: 4.138

Review 6.  Endosomal pH in neuronal signaling and synaptic transmission: role of Na(+)/H(+) exchanger NHE5.

Authors:  Graham H Diering; Masayuki Numata
Journal:  Front Physiol       Date:  2014-01-13       Impact factor: 4.566

7.  [3H]ethylpropylamiloride, a radio-labelled diuretic for the analysis of the Na+/H+ exchange system. Its use with kidney cell membranes.

Authors:  P Vigne; C Frelin; M Audinot; M Borsotto; E J Cragoe; M Lazdunski
Journal:  EMBO J       Date:  1984-11       Impact factor: 11.598

8.  The regulation of cytosolic pH in isolated presynaptic nerve terminals from rat brain.

Authors:  D A Nachshen; P Drapeau
Journal:  J Gen Physiol       Date:  1988-02       Impact factor: 4.086

9.  Presynaptic pH and vesicle fusion in Drosophila larvae neurones.

Authors:  Lesley Caldwell; Peter Harries; Sebastian Sydlik; Christof J Schwiening
Journal:  Synapse       Date:  2013-06-03       Impact factor: 2.562
  9 in total

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