Literature DB >> 632934

Radionuclide imaging of primary renal-cell carcinoma by I-131-labeled antitumor antibody.

P Belitsky, T Ghose, J Aquino, S T Norvell, A H Blair.   

Abstract

A goat antibody against human renal-cell carcinoma reacted on immunofluorescence with renal-cell carcinomas from 20 patients, but not with normal adult human tissues, including kidney. After i.v. administration the I-131-linked antibody showed preferential tumor localization in six of seven patients with primary renal carcinoma. Labeled antitumor antibodies may have the specificity for tumor imaging that current radiopharmaceuticals lack.

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Year:  1978        PMID: 632934

Source DB:  PubMed          Journal:  J Nucl Med        ISSN: 0161-5505            Impact factor:   10.057


  3 in total

1.  Is there a role for radioimmunolocalization in diagnosis of intracranial malignancies?: discussion paper.

Authors:  J T Kemshead; D H Jones; A Goldman; R B Richardson; H B Coakham
Journal:  J R Soc Med       Date:  1984-10       Impact factor: 5.344

2.  Echinococcus granulosus: the potential use of specific radiolabelled antibodies in diagnosis by immunoscintigraphy.

Authors:  M T Rogan; D L Morris; D I Pritchard; A C Perkins
Journal:  Clin Exp Immunol       Date:  1990-05       Impact factor: 4.330

3.  Scintigraphy and distribution of labeled antibodies in rats with tumors.

Authors:  J G Sharp; J W Osborne; H F Cheng; K L Coop; G R Zimmerman
Journal:  Eur J Nucl Med       Date:  1982
  3 in total

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