Literature DB >> 6329084

Evaluation of lithium as an inhibitory agent of herpes simplex virus in cell cultures and during reactivation of latent infection in rabbits.

M D Trousdale, Y J Gordon, A C Peters, T I Gropen, E Nelson, A B Nesburn.   

Abstract

Lithium carbonate inhibited plaque formation of herpes simplex virus types 1 and 2 in rabbit kidney and Vero cells (50% effective dose, 435.5 to 490 micrograms/ml). Plasma lithium levels of 67 to 134 micrograms/ml were achieved by oral therapy in rabbits. However, neither ocular virus shedding nor virus-positive trigeminal ganglia were reduced after intentional reactivation of latent herpes simplex virus infection.

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Year:  1984        PMID： 6329084      PMCID： PMC185570          DOI： 10.1128/AAC.25.4.522

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  11 in total

1.  Accumulation of lithium in the particulate fraction of rat brain following its long-term administration.

Authors:  S Christensen
Journal:  J Neurochem       Date:  1974-12       Impact factor: 5.372

2.  Intracellular lithium concentration and clinical response: towards a membrane theory of depression.

Authors:  J Mendels; A Frazer
Journal:  J Psychiatr Res       Date:  1973-06       Impact factor: 4.791

3.  Determination of plasma and erythrocyte lithium concentrations by atomic absorption spectrophotometry.

Authors:  G H Hisayasu; J L Cohen; R W Nelson
Journal:  Clin Chem       Date:  1977-01       Impact factor: 8.327

Review 4.  Biology of the lithium ion.

Authors:  G N Pandey; J M Davis
Journal:  Adv Exp Med Biol       Date:  1980       Impact factor: 2.622

5.  Immunopotentiation and inhibition of herpes virus activation during therapy with lithium carbonate.

Authors:  J Lieb
Journal:  Med Hypotheses       Date:  1981-07       Impact factor: 1.538

6.  Intracellular lithium and clinical response.

Authors:  R C Casper; G Pandey; L Gosenfeld; J M Davis
Journal:  Lancet       Date:  1976-08-21       Impact factor: 79.321

7.  Remission of recurrent herpes infection during therapy with lithium.

Authors:  J Lieb
Journal:  N Engl J Med       Date:  1979-10-25       Impact factor: 91.245

8.  The effect of lithium chloride on the replication of herpes simplex virus.

Authors:  G R Skinner; C Hartley; A Buchan; L Harper; P Gallimore
Journal:  Med Microbiol Immunol       Date:  1980       Impact factor: 3.402

9.  Evaluation of the antiherpetic activity of 2'-fluoro-5-iodo-ara-C in rabbit eyes and cell cultures.

Authors:  M D Trousdale; A B Nesburn; K A Watanabe; J J Fox
Journal:  Invest Ophthalmol Vis Sci       Date:  1981-12       Impact factor: 4.799

10.  Activity of 1-(2'-fluoro-2'-deoxy-beta-D-arabinofuranosyl)thymine against herpes simplex virus in cell cultures and rabbit eyes.

Authors:  M D Trousdale; A B Nesburn; T L Su; C Lopez; K A Watanabe; J J Fox
Journal:  Antimicrob Agents Chemother       Date:  1983-06       Impact factor: 5.191
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  1 in total

Review 1.  Lithium's antiviral effects: a potential drug for CoViD-19 disease?

Authors:  Andrea Murru; Mirko Manchia; Tomas Hajek; René E Nielsen; Janusz K Rybakowski; Gabriele Sani; Thomas G Schulze; Leonardo Tondo; Michael Bauer
Journal:  Int J Bipolar Disord       Date:  2020-05-20
  1 in total

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