Literature DB >> 6328656

Corticotropin-releasing factor receptors in rat forebrain: autoradiographic identification.

E B De Souza, M H Perrin, T R Insel, J Rivier, W W Vale, M J Kuhar.   

Abstract

Corticotropin-releasing factor (CRF) receptors were identified in rat forebrain by autoradiography with an iodine-125-labeled analog of ovine CRF substituted with norleucine and tyrosine at amino acid residues 21 and 32, respectively. High-affinity receptors for CRF were found in discrete areas of rat forebrain, including laminae I and IV of the neocortex, the external layer of the medium eminence, the lateral nucleus of the amygdala, and the striatum. These results are consistent with earlier findings on the immunohistochemical distribution of CRF and suggest that endogenous CRF has a physiological role in regulating activity of the central nervous system.

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Year:  1984        PMID： 6328656     DOI： 10.1126/science.6328656

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  30 in total

1.  Effect of corticotropin releasing factor injected into the median eminence on growth hormone secretion in male rats.

Authors:  J Frias; E Ruiz; E Ortega
Journal:  Neurochem Res       Date:  1999-06       Impact factor: 3.996

Review 2.  Minireview: CRF and Wylie Vale: a story of 41 amino acids and a Texan with grit.

Authors:  Tracy L Bale; Alon Chen
Journal:  Endocrinology       Date:  2012-04-04       Impact factor: 4.736

3.  Morphological demonstration and quantification of TSH binding sites in neoplastic and non-neoplastic thyroid tissues. An autoradiographic study using 125I-labelled thyrotropin.

Authors:  S Schröder; H W Müller-Gärtner; R Schroiff; P Schmiegelow; A Niendorf; W Böcker
Journal:  Virchows Arch A Pathol Anat Histopathol       Date:  1986

4.  Expression cloning of a human corticotropin-releasing-factor receptor.

Authors:  R Chen; K A Lewis; M H Perrin; W W Vale
Journal:  Proc Natl Acad Sci U S A       Date:  1993-10-01       Impact factor: 11.205

5.  Effect of CRF injected into the median eminence on GH secretion in female rats under different steroid status.

Authors:  A Puertas; J Frias; E Ruiz; E Ortega
Journal:  Neurochem Res       Date:  1996-08       Impact factor: 3.996

6.  Effect of corticotropin releasing factor (CRF) injected into the median eminence on LH secretion in male rats.

Authors:  J Frias; A Puertas; E Ruiz; E Ortega
Journal:  Neurochem Res       Date:  1997-02       Impact factor: 3.996

Review 7.  Regulatory peptide receptors: visualization by autoradiography.

Authors:  J M Palacios; M M Dietl
Journal:  Experientia       Date:  1987-07-15

8.  Identification of a second corticotropin-releasing factor receptor gene and characterization of a cDNA expressed in heart.

Authors:  M Perrin; C Donaldson; R Chen; A Blount; T Berggren; L Bilezikjian; P Sawchenko; W Vale
Journal:  Proc Natl Acad Sci U S A       Date:  1995-03-28       Impact factor: 11.205

9.  Type 1 corticotropin-releasing factor receptor expression reported in BAC transgenic mice: implications for reconciling ligand-receptor mismatch in the central corticotropin-releasing factor system.

Authors:  Nicholas J Justice; Zung Fan Yuan; Paul E Sawchenko; Wylie Vale
Journal:  J Comp Neurol       Date:  2008-12-01       Impact factor: 3.215

Review 10.  Physiological and neurochemical aspects of corticotropin-releasing factor actions in the brain: the role of the locus coeruleus.

Authors:  H Lehnert; C Schulz; K Dieterich
Journal:  Neurochem Res       Date:  1998-08       Impact factor: 3.996
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