Literature DB >> 632840

Herpes simplex virus antibodies in patients with Parkinson's disease.

R J Marttila, U K Rinne.   

Abstract

Sera from 40 patients with idiopathic Parkinson's disease and their age- and sex-matched controls were assayed for immunoglobulin G (IgG) antibodies against herpes simplex virus (HSV) type 1-induced cell surface antigens with the indirect immunofluorescent test. An increased level of HSV antibodies was found among the patients with Parkinson's disease when the distribution of titres (P less than 0.001), the mean titres (P less than 0.001), or the mean paired titre difference (P less than 0.001) was compared with the controls. This may suggest a part of HSV in the pathogenesis of Parkinson's disease. Alternatively, the increased HSV antibody response might be an epiphenomenon indirectly associated with Parkinson's disease.

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Year:  1978        PMID： 632840     DOI： 10.1016/0022-510x(78)90017-5

Source DB:  PubMed          Journal:  J Neurol Sci        ISSN： 0022-510X            Impact factor:   3.181


  6 in total

Review 1.  Intranasal administration of neurotoxicants in animals: support for the olfactory vector hypothesis of Parkinson's disease.

Authors:  Rui D S Prediger; Aderbal S Aguiar; Filipe C Matheus; Roger Walz; Layal Antoury; Rita Raisman-Vozari; Richard L Doty
Journal:  Neurotox Res       Date:  2011-10-15       Impact factor: 3.911

2.  Immunocytochemical investigations on the presence of neuron-specific antibodies in the CSF of Parkinson's disease cases.

Authors:  A McRae-Degueurce; L Rosengren; K Haglid; S Bööj; C G Gottfries; A C Granérus; A Dahlström
Journal:  Neurochem Res       Date:  1988-07       Impact factor: 3.996

Review 3.  A role for viral infections in Parkinson's etiology?

Authors:  Laura K Olsen; Eilis Dowd; Declan P McKernan
Journal:  Neuronal Signal       Date:  2018-04-16

Review 4.  Inflammation, Infectious Triggers, and Parkinson's Disease.

Authors:  Elisa Caggiu; Giannina Arru; Sepideh Hosseini; Magdalena Niegowska; GianPietro Sechi; Ignazio Roberto Zarbo; Leonardo A Sechi
Journal:  Front Neurol       Date:  2019-02-19       Impact factor: 4.003

Review 5.  Post-COVID-19 Parkinsonism and Parkinson's Disease Pathogenesis: The Exosomal Cargo Hypothesis.

Authors:  Dimitrios S Mysiris; George D Vavougios; Eirini Karamichali; Stamatia Papoutsopoulou; Vasileios T Stavrou; Eirini Papayianni; Stylianos Boutlas; Theodoros Mavridis; Pelagia Foka; Sotirios G Zarogiannis; Konstantinos Gourgoulianis; Georgia Xiromerisiou
Journal:  Int J Mol Sci       Date:  2022-08-28       Impact factor: 6.208

6.  A Possible Role for HSV-1-Specific Humoral Response and PILRA rs1859788 Polymorphism in the Pathogenesis of Parkinson's Disease.

Authors:  Simone Agostini; Roberta Mancuso; Andrea S Costa; Lorenzo A Citterio; Franca R Guerini; Mario Meloni; Jorge Navarro; Mario Clerici
Journal:  Vaccines (Basel)       Date:  2021-06-22
  6 in total

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