| Literature DB >> 6328343 |
L McLoughlin, S Tomlin, A Grossman, N Lytras, A V Schally, D Coy, G M Besser, L H Rees.
Abstract
A prompt rise in circulating immunoreactive N- and C-terminal lipotrophin (LPH) accompanied the increase in ACTH when 100 micrograms CRF-41 was given to 6 normal male subjects. Chromatography of the basal and peak 15-min values showed that there was an equimolar increase in beta-LPH and beta-endorphin, to cause parallel release of ACTH, beta-endorphin and beta-LPH from the pro-opiocortin precursor.Entities:
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Year: 1984 PMID: 6328343 DOI: 10.1159/000123904
Source DB: PubMed Journal: Neuroendocrinology ISSN: 0028-3835 Impact factor: 4.914