Literature DB >> 6328343

CRF-41 stimulates the release of beta-lipotrophin and beta-endorphin in normal human subjects.

L McLoughlin, S Tomlin, A Grossman, N Lytras, A V Schally, D Coy, G M Besser, L H Rees.   

Abstract

A prompt rise in circulating immunoreactive N- and C-terminal lipotrophin (LPH) accompanied the increase in ACTH when 100 micrograms CRF-41 was given to 6 normal male subjects. Chromatography of the basal and peak 15-min values showed that there was an equimolar increase in beta-LPH and beta-endorphin, to cause parallel release of ACTH, beta-endorphin and beta-LPH from the pro-opiocortin precursor.

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Year:  1984        PMID: 6328343     DOI: 10.1159/000123904

Source DB:  PubMed          Journal:  Neuroendocrinology        ISSN: 0028-3835            Impact factor:   4.914


  3 in total

1.  Corticotropin releasing hormone stimulation test: diagnostic aspects in Cushing's syndrome.

Authors:  M Boscaro; A Rampazzo; N Sonino; G Merola; M Scanarini; F Mantero
Journal:  J Endocrinol Invest       Date:  1987-06       Impact factor: 4.256

2.  Isolation and amino acid sequence of corticotropin-releasing factor from pig hypothalami.

Authors:  M Patthy; J Horvath; M Mason-Garcia; B Szoke; D H Schlesinger; A V Schally
Journal:  Proc Natl Acad Sci U S A       Date:  1985-12       Impact factor: 11.205

3.  Potentiation of the hCRF-induced release of ACTH in man by an opioid antagonist.

Authors:  H Ehrenreich; C Kolmar; O A Müller; F D Goebel
Journal:  Klin Wochenschr       Date:  1987-05-15
  3 in total

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