Literature DB >> 632812

Radioimmunoassay and some properties of human antibodies to hepatitis B core antigen.

A R Neurath, W Szmuness, C E Stevens, N Strick, E J Harley.   

Abstract

A solid-phase radioimmunoassay for antibodies to hepatitis B core antigen (anti-HBc) is described. Polystyrene beads coated with anti-HBc, hepatitis B core antigen prepared from pooled sera of humans infected with hepatitis B virus (HBV) and 125I-labelled anti-HBc were used for the test. Distinct patterns of development and changes of anti-HBc and their immunologic properties are all related to variations of other markers specific for HBV infections. Knowledge concerning the detailed features of the immune response to hepatitis B core antigen may provide deeper insight into the pathogenesis of HBV infections.

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Year:  1978        PMID： 632812     DOI： 10.1099/0022-1317-38-3-549

Source DB:  PubMed          Journal:  J Gen Virol        ISSN： 0022-1317            Impact factor:   3.891


  3 in total

1.  Specificity of antibodies elicited by a synthetic peptide having a sequence in common with a fragment of a virus protein, the hepatitis B surface antigen.

Authors:  A R Neurath; S B Kent; N Strick
Journal:  Proc Natl Acad Sci U S A       Date:  1982-12       Impact factor: 11.205

2.  Radioimmunoassays of hidden viral antigens.

Authors:  A R Neurath; N Strick; L Baker; S Krugman
Journal:  Proc Natl Acad Sci U S A       Date:  1982-07       Impact factor: 11.205

3.  Viral hepatitis A and B in hemodialysed patients.

Authors:  K Gmelin; B von Ehrlich; B Kommerell; E Ritz; J Bommer
Journal:  Klin Wochenschr       Date:  1980-04-01
  3 in total

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