| Literature DB >> 6326980 |
A W McClurkin, E T Littledike, R C Cutlip, G H Frank, M F Coria, S R Bolin.
Abstract
Inoculation of bovine virus diarrhea virus into 58 to 125 day old fetuses of bovine virus diarrhea virus seropositive pregnant cows, or inoculation of bovine virus diarrhea virus into seronegative cows 42 to 114 days pregnant, may produce clinically normal calves which are persistently infected with the specific isolate of bovine virus diarrhea virus yet seronegative to the homologous and heterologous isolates. Reinoculation of these persistently infected cattle with their homologous isolate produced no neutralizing antibody response to bovine virus diarrhea virus. These persistently infected cattle were immunocompetent as they developed neutralizing serotiters to infectious bovine rhinotracheitis, parainfluenza-3 viruses and agglutinating serotiters to Pasteurella hemolytica .Entities:
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Year: 1984 PMID: 6326980 PMCID: PMC1236029
Source DB: PubMed Journal: Can J Comp Med ISSN: 0008-4050