Literature DB >> 6326658

The structural gene for transferrin (TF) maps to 3q21----3qter.

C Huerre, G Uzan, K H Grzeschik, D Weil, M Levin, M C Hors-Cayla, J Boué, A Kahn, C Junien.   

Abstract

A cloned human cDNA for transferrin (TF) was used as hybridization probe in analysing a series of rodent x human somatic cell hybrids for the presence of human TF sequences. The assignment to chromosome 3 was further refined to region 3q21----3qter using hybrids that carried a translocated chromosome 3 and fibroblasts from a patient trisomic for this region. The gene for TF therefore maps to the same region as the gene for transferrin receptor (TFR) thereby defining an iron transport region on 3q2 to which the transferrin-related tumor associated antigen p97 may also belong. It follows that the genes for pseudocholinesterase (CHE1), ceruleoplasmin (CP) and alpha-2HS-glycoprotein (A2HS) which belong to the, as yet unassigned, linkage group of TF, now also map to chromosome 3 in man.

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Year:  1984        PMID： 6326658

Source DB:  PubMed          Journal:  Ann Genet        ISSN： 0003-3995


  8 in total

Review 1.  Genes other than BRCA1 and BRCA2 involved in breast cancer susceptibility.

Authors:  M M de Jong; I M Nolte; G J te Meerman; W T A van der Graaf; J C Oosterwijk; J H Kleibeuker; M Schaapveld; E G E de Vries
Journal:  J Med Genet       Date:  2002-04       Impact factor: 6.318

Review 2.  T-cell clones and T-cell receptors.

Authors:  F W Fitch
Journal:  Microbiol Rev       Date:  1986-03

Review 3.  Molecular biological search for human genes encoding cholinesterases.

Authors:  H Soreq; A Gnatt
Journal:  Mol Neurobiol       Date:  1987 Spring-Summer       Impact factor: 5.590

4.  Chromosomal assignment of two myosin alkali light-chain genes encoding the ventricular/slow skeletal muscle isoform and the atrial/fetal muscle isoform (MYL3, MYL4).

Authors:  O Cohen-Haguenauer; P J Barton; N Van Cong; A Cohen; M Masset; M Buckingham; J Frézal
Journal:  Hum Genet       Date:  1989-02       Impact factor: 4.132

5.  The p97 antigen is mapped to the q24-qter region of chromosome 3; the same region as the transferrin receptor.

Authors:  P A Seligman; C D Butler; E J Massey; J A Kaur; J P Brown; G D Plowman; Y Miller; C Jones
Journal:  Am J Hum Genet       Date:  1986-04       Impact factor: 11.025

6.  Chromosomal localization of ceruloplasmin and transferrin genes in laboratory rats, mice and in man by hybridization with specific DNA probes.

Authors:  V S Baranov; A L Schwartzman; V N Gorbunova; V S Gaitskhoki; N B Rubtsov; N A Timchenko; S A Neifakh
Journal:  Chromosoma       Date:  1987       Impact factor: 4.316

7.  Human cholinesterase genes localized by hybridization to chromosomes 3 and 16.

Authors:  H Soreq; R Zamir; D Zevin-Sonkin; H Zakut
Journal:  Hum Genet       Date:  1987-12       Impact factor: 4.132

8.  Transferrin subtypes in 51 Danish patients with hereditary haemochromatosis and in 847 normal subjects.

Authors:  N Milman; H Eiberg; M Thymann; K Fenger
Journal:  Hum Genet       Date:  1992-02       Impact factor: 4.132
  8 in total

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