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Literature DB >> 6325579

Analysis of sodium current fluctuations in the cut-open squid giant axon.

Abstract

Patch pipettes were used to record the current arising from small populations of sodium channels in voltage-clamped cut-open squid axons. The current fluctuations associated with the time-variant sodium conductance were analyzed with nonstationary statistical techniques in order to obtain an estimate for the conductance of a single sodium channel. The results presented support the notion that the open sodium channel in the squid axon has only one value of conductance, 3.5 pS.

Entities: Chemical

Mesh：

Substances：
Ion Channels
Sodium

Year: 1984 PMID： 6325579 PMCID： PMC2215630 DOI： 10.1085/jgp.83.2.133

Source DB: PubMed Journal: J Gen Physiol ISSN： 0022-1295 Impact factor: 4.086

11 in total

1. Potassium and sodium ion current noise in the membrane of the squid giant axon.

Authors: F Conti; L J De Felice; E Wanke
Journal: J Physiol Date: 1975-06 Impact factor: 5.182

2. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches.

Authors: O P Hamill; A Marty; E Neher; B Sakmann; F J Sigworth
Journal: Pflugers Arch Date: 1981-08 Impact factor: 3.657

3. Unitary current through sodium channel and anomalous rectifier channel estimated from transient current noise in the tunicate egg.

Authors: H Ohmori
Journal: J Physiol Date: 1981-02 Impact factor: 5.182

4. Batrachotoxin-modified sodium channels from squid optic nerve in planar bilayers. Ion conduction and gating properties.

Authors: M I Behrens; A Oberhauser; F Bezanilla; R Latorre
Journal: J Gen Physiol Date: 1989-01 Impact factor: 4.086

4 in total

Analysis of sodium current fluctuations in the cut-open squid giant axon.

1. Potassium and sodium ion current noise in the membrane of the squid giant axon.

2. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches.

3. Unitary current through sodium channel and anomalous rectifier channel estimated from transient current noise in the tunicate egg.

4. The variance of sodium current fluctuations at the node of Ranvier.

5. Single Na+ channel currents observed in cultured rat muscle cells.

6. Modification of single Na+ channels by batrachotoxin.

Review 7. Fluctuation of Na and K currents in excitable membranes.

8. Current recorded from a cut-open giant axon under voltage clamp.

9. Currents recorded through small areas of squid axon membrane with an internal virtual ground voltage clamp.

10. Sodium channels in nerve apparently have two conductance states.

1. The conductance and density of sodium channels in the cut-open squid giant axon.

2. Single sodium channels from the squid giant axon.

3. Ion permeation in normal and batrachotoxin-modified Na+ channels in the squid giant axon.

4. Batrachotoxin-modified sodium channels from squid optic nerve in planar bilayers. Ion conduction and gating properties.