Literature DB >> 6325242

Evolution and structure of two ADP-ribosylation enterotoxins, Escherichia coli heat-labile toxin and cholera toxin.

T Yamamoto, T Nakazawa, T Miyata, A Kaji, T Yokota.   

Abstract

Nucleotide sequence comparisons of the heat-labile enterotoxin (LTh) genes of E. coli pathogenic for humans with cholera toxin (CT) genes suggest that the two toxin genes have evolved from a common ancestry by a series of single base changes, while conserving the catalytic fragment A1 (ADP-ribose transferase). Based on the local hydrophilicity profiles of LTh and CT peptides, a transmembrane segment appears to be present in A1 in both toxins.

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Year:  1984        PMID： 6325242     DOI： 10.1016/0014-5793(84)80326-9

Source DB:  PubMed          Journal:  FEBS Lett        ISSN： 0014-5793            Impact factor:   4.124


  24 in total

1.  Cloning and expression of the Salmonella enterotoxin gene.

Authors:  A K Chopra; C W Houston; J W Peterson; R Prasad; J J Mekalanos
Journal:  J Bacteriol       Date:  1987-11       Impact factor: 3.490

2.  Site-specific mutagenesis of the catalytic subunit of cholera toxin: substituting lysine for arginine 7 causes loss of activity.

Authors:  W N Burnette; V L Mar; B W Platler; J D Schlotterbeck; M D McGinley; K S Stoney; M F Rohde; H R Kaslow
Journal:  Infect Immun       Date:  1991-11       Impact factor: 3.441

3.  Mutations in the A subunit affect yield, stability, and protease sensitivity of nontoxic derivatives of heat-labile enterotoxin.

Authors:  C Magagnoli; R Manetti; M R Fontana; V Giannelli; M M Giuliani; R Rappuoli; M Pizza
Journal:  Infect Immun       Date:  1996-12       Impact factor: 3.441

4.  Cloning and nucleotide sequence of the gene (trh) encoding the hemolysin related to the thermostable direct hemolysin of Vibrio parahaemolyticus.

Authors:  M Nishibuchi; T Taniguchi; T Misawa; V Khaeomanee-Iam; T Honda; T Miwatani
Journal:  Infect Immun       Date:  1989-09       Impact factor: 3.441

5.  Molecular cloning of pertussis toxin genes.

Authors:  C Locht; P A Barstad; J E Coligan; L Mayer; J J Munoz; S G Smith; J M Keith
Journal:  Nucleic Acids Res       Date:  1986-04-25       Impact factor: 16.971

6.  Inhibition of cholera toxin binding to membrane receptors by pig gastric mucin-derived glycopeptides: differential effect depending on the ABO blood group antigenic determinants.

Authors:  C G Monferran; G A Roth; F A Cumar
Journal:  Infect Immun       Date:  1990-12       Impact factor: 3.441

7.  Cloning, sequencing, and expression of a gene encoding a 100-kilodalton mosquitocidal toxin from Bacillus sphaericus SSII-1.

Authors:  T Thanabalu; J Hindley; J Jackson-Yap; C Berry
Journal:  J Bacteriol       Date:  1991-05       Impact factor: 3.490

8.  Calcium transport affinity, ion competition and cholera toxin effects on cytosolic Ca concentration.

Authors:  D D Maenz; S E Gabriel; G W Forsyth
Journal:  J Membr Biol       Date:  1987       Impact factor: 1.843

9.  Evolutionary origin of pathogenic determinants in enterotoxigenic Escherichia coli and Vibrio cholerae O1.

Authors:  T Yamamoto; T Gojobori; T Yokota
Journal:  J Bacteriol       Date:  1987-03       Impact factor: 3.490

10.  Effect of substitution of glycine for arginine at position 146 of the A1 subunit on biological activity of Escherichia coli heat-labile enterotoxin.

Authors:  K Okamoto; K Okamoto; A Miyama; T Tsuji; T Honda; T Miwatani
Journal:  J Bacteriol       Date:  1988-05       Impact factor: 3.490
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