Literature DB >> 6325222

Protective effect of cAMP on tumor promoter-mediated inhibition of cell-cell communication.

Y Kanno, T Enomoto, Y Shiba, H Yamasaki.   

Abstract

The formation and maintenance of electrical cell coupling is inhibited by 100 ng/ml 12-O-tetradecanoylphorbol-13-acetate (TPA). This inhibition could be prevented by db-cAMP and aminophylline when added together with TPA, though they did not restore the cell coupling once it had already been blocked by TPA. It is suggested that db-cAMP affects the early membrane effects of TPA in FL cells.

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Year:  1984        PMID: 6325222     DOI: 10.1016/0014-4827(84)90227-1

Source DB:  PubMed          Journal:  Exp Cell Res        ISSN: 0014-4827            Impact factor:   3.905


  7 in total

Review 1.  Gap junction channel gating modulated through protein phosphorylation.

Authors:  Alonso P Moreno; Alan F Lau
Journal:  Prog Biophys Mol Biol       Date:  2007-03-15       Impact factor: 3.667

2.  Characterization of a rat liver epithelial cell line to detect inhibitors of metabolic cooperation.

Authors:  C Jone; J E Trosko; C C Chang
Journal:  In Vitro Cell Dev Biol       Date:  1987-03

3.  Study of the biological effects of theophylline on V79 cells: viability, membrane permeability, and metabolic cooperation.

Authors:  A Gabelova; D Slamenova; T Bohusova
Journal:  Cell Biol Toxicol       Date:  1991-04       Impact factor: 6.691

4.  Turnover and phosphorylation dynamics of connexin43 gap junction protein in cultured cardiac myocytes.

Authors:  D W Laird; K L Puranam; J P Revel
Journal:  Biochem J       Date:  1991-01-01       Impact factor: 3.857

5.  Induction of glucagon sensitivity in a transformed kidney cell line by prostaglandin E2 and its inhibition by epidermal growth factor.

Authors:  M C Lin; F J Darfler; S K Beckner
Journal:  Mol Cell Biol       Date:  1987-12       Impact factor: 4.272

6.  Hyperphosphorylation of N-60, a protein structurally and immunologically related to nucleolin after tumour-promoter treatment.

Authors:  O G Issinger; T Martin; W W Richter; M Olson; H Fujiki
Journal:  EMBO J       Date:  1988-06       Impact factor: 11.598

7.  Herbimycin A suppresses the reduction of gap-junctional intercellular communication induced by tumor-promoting phorbol ester in 3T3-L1 cells.

Authors:  Y Sasaki; Y Shiba; C Hirono; Y Kanno; T Takeuchi; K Umezawa
Journal:  Jpn J Cancer Res       Date:  1989-09
  7 in total

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