Literature DB >> 6324946

Prenatal diagnosis of homozygous alpha thalassaemia by direct DNA analysis of uncultured amniotic fluid cells.

V Chan, A Ghosh, T K Chan, V Wong, D Todd.   

Abstract

Prenatal diagnosis of homozygous alpha thalassaemia was performed in eight successive patients at risk using DNA from uncultured amniotic fluid cells. The presence of alpha gene was determined by restriction endonuclease mapping and hybridisation with cloned alpha and beta globin probes. This method is reliable and may be performed at 16 weeks of gestation.

Entities:  

Mesh：

Substances：

Year:  1984        PMID： 6324946      PMCID： PMC1440955          DOI： 10.1136/bmj.288.6427.1327

Source DB:  PubMed          Journal:  Br Med J (Clin Res Ed)        ISSN： 0267-0623


  14 in total

1.  Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

Authors:  P W Rigby; M Dieckmann; C Rhodes; P Berg
Journal:  J Mol Biol       Date:  1977-06-15       Impact factor: 5.469

2.  alpha-Globin gene organisation in blacks precludes the severe form of alpha-thalassaemia.

Authors:  A M Dozy; Y W Kan; S H Embury; W C Mentzer; W C Wang; B Lubin; J R Davis; H M Koenig
Journal:  Nature       Date:  1979-08-16       Impact factor: 49.962

3.  Prenatal diagnosis of homozygous alpha-thalassemia.

Authors:  A M Dozy; E N Forman; D N Abuelo; G Barsel-Bowers; M J Mahoney; B G Forget; Y W Kan
Journal:  JAMA       Date:  1979-04-13       Impact factor: 56.272

4.  Genetic lesion in homozygous alpha thalassaemia (hydrops fetalis).

Authors:  J M Taylor; A Dozy; Y W Kan; H E Varmus; L E Lie-Injo; J Ganesan; D Todd
Journal:  Nature       Date:  1974-10-04       Impact factor: 49.962

5.  The severe form of alpha thalassaemia is caused by a haemoglobin gene deletion.

Authors:  S Ottolenghi; W G Lanyon; J Paul; R Williamson; D J Weatherall; J B Clegg; J Pritchard; S Pootrakul; W H Boon
Journal:  Nature       Date:  1974-10-04       Impact factor: 49.962

6.  Alpha-thalassaemia in Chinese: cord blood studies.

Authors:  D Todd; M C Lai; C A Braga; H N Soo
Journal:  Br J Haematol       Date:  1969-06       Impact factor: 6.998

7.  Alpha- and beta-thalassemia in Thailand.

Authors:  P Wasi; S Na-Nakorn; S Pootrakul; M Sookanek; P Disthasongchan; V Panich; M Pornpatkul
Journal:  Ann N Y Acad Sci       Date:  1969-11-20       Impact factor: 5.691

8.  Prenatal diagnosis of hemoglobinopathies.

Authors:  Y W Kan; R F Trecartin; A M Dozy
Journal:  Ann N Y Acad Sci       Date:  1980       Impact factor: 5.691

9.  Antenatal diagnosis of sickle-cell anaemia by D.N.A. analysis of amniotic-fluid cells.

Authors:  Y W Kan; A M Dozy
Journal:  Lancet       Date:  1978-10-28       Impact factor: 79.321

10.  Diagnosis of homozygous alpha-thalassemia in cultured amniotic-fluid fibroblasts.

Authors:  V Wong; H K Ma; D Todd; M S Golbus; A M Dozy; Y W Kan
Journal:  N Engl J Med       Date:  1978-03-23       Impact factor: 91.245
View more
  1 in total

1.  Fetal tissue sampling. The San Francisco experience with 190 pregnancies.

Authors:  M S Golbus; K F McGonigle; J D Goldberg; R A Filly; P W Callen; R L Anderson
Journal:  West J Med       Date:  1989-04
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.