| Literature DB >> 6324665 |
W L Albritton, I W Maclean, L A Slaney, A R Ronald, H G Deneer.
Abstract
Clinical isolates of Haemophilus ducreyi were shown to be resistant to tetracycline. Resistance was associated in some strains with a 30-megadalton plasmid capable of transferring resistance in conjugative matings with other strains of H. ducreyi and other species of Haemophilus. Restriction endonuclease digestion patterns suggest a relationship between H. ducreyi plasmids and other tetracycline resistance plasmids in Haemophilus. The presence of plasmid-mediated resistance to the tetracyclines limits the use of these agents for the treatment of chancroid.Entities:
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Year: 1984 PMID: 6324665 PMCID: PMC185471 DOI: 10.1128/AAC.25.2.187
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191