Literature DB >> 6324567

Ascorbic acid: a scavenger of superoxide radical.

S Som, C Raha, I B Chatterjee.   

Abstract

The second order rate constant for the reaction between ascorbic acid and superoxide at pH 7.4 using the xanthine-xanthine oxidase system was estimated to be 5.4 x 10(6) M-1 sec-1. The results indicate that the efficacies of superoxide dismutase and ascorbic acid for catalyzing the decay of superoxide radical in animal tissues are similar. The significance of ascorbic acid as a scavenger of superoxide is discussed from the point of view of evolution of ascorbic acid synthesizing capacity in the terrestrial vertebrates.

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Year:  1983        PMID： 6324567

Source DB:  PubMed          Journal:  Acta Vitaminol Enzymol        ISSN： 0300-8924


  13 in total

1.  Cell multiplication of an ascites tumour in the presence of superoxide dismutase and catalase.

Authors:  F S Liotti; P Guerrieri; A R Menghini; F Pezzetti
Journal:  J Cancer Res Clin Oncol       Date:  1986       Impact factor: 4.553

2.  Vitamin C increases DNA breaks and suppresses DNA damage-independent activation of ATM by bleomycin.

Authors:  Blazej Rubis; Michal W Luczak; Casey Krawic; Anatoly Zhitkovich
Journal:  Free Radic Biol Med       Date:  2019-03-26       Impact factor: 7.376

3.  Protective role of ascorbic acid against lipid peroxidation and myocardial injury.

Authors:  S Chakrabarty; A Nandi; C K Mukhopadhyay; I B Chatterjee
Journal:  Mol Cell Biochem       Date:  1992-04       Impact factor: 3.396

4.  A critical role of gastric mucosal ascorbic acid in the progression of acute gastric mucosal lesions induced by compound 48/80 in rats.

Authors:  Yoshio Kamiya; Yoshiji Ohta; Yoichiro Imai; Tomiyasu Arisawa; Hiroshi Nakano
Journal:  World J Gastroenterol       Date:  2005-03-07       Impact factor: 5.742

5.  Effects of vitamin C and of a cell permeable superoxide dismutase mimetic on acute lipoprotein induced endothelial dysfunction in rabbit aortic rings.

Authors:  L Fontana; K L McNeill; J M Ritter; P J Chowienczyk
Journal:  Br J Pharmacol       Date:  1999-02       Impact factor: 8.739

6.  Biological signaling by small inorganic molecules.

Authors:  Debashree Basudhar; Lisa A Ridnour; Robert Cheng; Aparna H Kesarwala; Julie Heinecke; David A Wink
Journal:  Coord Chem Rev       Date:  2016-01-01       Impact factor: 22.315

7.  ROS generated by pollen NADPH oxidase provide a signal that augments antigen-induced allergic airway inflammation.

Authors:  Istvan Boldogh; Attila Bacsi; Barun K Choudhury; Nilesh Dharajiya; Rafeul Alam; Tapas K Hazra; Sankar Mitra; Randall M Goldblum; Sanjiv Sur
Journal:  J Clin Invest       Date:  2005-08       Impact factor: 14.808

8.  Protective effect of ascorbic acid against lipid peroxidation and oxidative damage in cardiac microsomes.

Authors:  M Mukhopadhyay; C K Mukhopadhyay; I B Chatterjee
Journal:  Mol Cell Biochem       Date:  1993-09-08       Impact factor: 3.396

9.  Involvement of H2O2 in superoxide-dismutase-induced enhancement of endothelium-dependent relaxation in rabbit mesenteric resistance artery.

Authors:  Takeo Itoh; Junko Kajikuri; Tomonori Hattori; Nobuyoshi Kusama; Tamao Yamamoto
Journal:  Br J Pharmacol       Date:  2003-05       Impact factor: 8.739

10.  Vitamin C improves endothelium-dependent vasodilation in patients with non-insulin-dependent diabetes mellitus.

Authors:  H H Ting; F K Timimi; K S Boles; S J Creager; P Ganz; M A Creager
Journal:  J Clin Invest       Date:  1996-01-01       Impact factor: 14.808
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