| Literature DB >> 6324248 |
Abstract
Chronic antidepressant treatment with classical and atypical antidepressant drugs and ECT leads to complex changes in the central adrenergic system, consisting of upregulation of alpha 1 and downregulation of alpha 2 and beta adrenoceptors. These changes may lead to a specific facilitation of neurotransmission in structures employing alpha 1 adrenoceptors, involved in the control of mood and emotions.Entities:
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Year: 1984 PMID: 6324248 DOI: 10.1055/s-2007-1017401
Source DB: PubMed Journal: Pharmacopsychiatry ISSN: 0176-3679 Impact factor: 5.788