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Literature DB >> 6323997

The locus of sequence-directed and protein-induced DNA bending.

Abstract

The bending locus of trypanosome kinetoplast DNA, identified by gel electrophoresis, has tracts of a simple repeat sequence (CA5-6 T) symmetrically distributed about it, with a repeat interval of 10 base pairs. The analogous bending induced when catabolite gene activating protein binds to its recognition sequence near the promoter of the Escherichia coli lac operon is centred on a site about 5-7 base pairs away from the centre of the protein binding site.

Entities: Gene Species

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Year: 1984 PMID： 6323997 DOI： 10.1038/308509a0

Source DB: PubMed Journal: Nature ISSN： 0028-0836 Impact factor: 49.962

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Cited

488 in total

1. The RAG1 homeodomain recruits HMG1 and HMG2 to facilitate recombination signal sequence binding and to enhance the intrinsic DNA-bending activity of RAG1-RAG2.

Authors: V Aidinis; T Bonaldi; M Beltrame; S Santagata; M E Bianchi; E Spanopoulou
Journal: Mol Cell Biol Date: 1999-10 Impact factor: 4.272

2. Solution structure and dynamics of the A-T tract DNA decamer duplex d(GGTAATTACC)2: implications for recognition by minor groove binding drugs.

Authors: C E Bostock-Smith; C A Laughton; M S Searle
Journal: Biochem J Date: 1999-08-15 Impact factor: 3.857

The locus of sequence-directed and protein-induced DNA bending.

1. The RAG1 homeodomain recruits HMG1 and HMG2 to facilitate recombination signal sequence binding and to enhance the intrinsic DNA-bending activity of RAG1-RAG2.

2. Solution structure and dynamics of the A-T tract DNA decamer duplex d(GGTAATTACC)2: implications for recognition by minor groove binding drugs.

3. Dynamic bending rigidity of a 200-bp DNA in 4 mM ionic strength: a transient polarization grating study.

4. Straightening of bulged RNA by the double-stranded RNA-binding domain from the protein kinase PKR.

5. The SKN-1 amino-terminal arm is a DNA specificity segment.

6. Global structure and mechanical properties of a 10-bp nucleosome positioning motif.

7. Interaction of nuclear proteins with intrinsically curved DNA in a matrix attachment region of a tobacco gene.

8. Poly(dA.dT) sequences exist as rigid DNA structures in nucleosome-free yeast promoters in vivo.

9. DNA binding by single HMG box model proteins.

10. DNA bending induced by DNA (cytosine-5) methyltransferases.