Literature DB >> 6323927

Tn4001: a gentamicin and kanamycin resistance transposon in Staphylococcus aureus.

B R Lyon, J W May, R A Skurray.   

Abstract

We describe a 4.5 kilobase transposon, Tn4001, which mediates resistance to gentamicin, tobramycin and kanamycin in Staphylococcus aureus. Originally detected in plasmid pSK1, Tn4001 was shown to undergo rec-independent transposition to the chromosome from this plasmid and from an inserted derivative of the plasmid pII147. Heteroduplexes between plasmids with and without Tn4001 demonstrated a characteristic stem and loop structure with inverted repeats of approx. 1.3 kilobases.

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Year:  1984        PMID： 6323927     DOI： 10.1007/bf00382099

Source DB:  PubMed          Journal:  Mol Gen Genet        ISSN： 0026-8925


  12 in total

1.  Penicillinase plasmids of Staphylococcus aureus: structural and evolutionary relationships.

Authors:  Z Shalita; E Murphy; R P Novick
Journal:  Plasmid       Date:  1980-05       Impact factor: 3.466

2.  Analysis of plasmids in nosocomial strains of multiple-antibiotic-resistant Staphylococcus aureus.

Authors:  B R Lyon; J W May; R A Skurray
Journal:  Antimicrob Agents Chemother       Date:  1983-06       Impact factor: 5.191

3.  Genetic translocation in Staphylococcus aureus.

Authors:  R P Novick; I Edelman; M D Schwesinger; A D Gruss; E C Swanson; P A Pattee
Journal:  Proc Natl Acad Sci U S A       Date:  1979-01       Impact factor: 11.205

4.  Nucleotide sequence and functional map of pC194, a plasmid that specifies inducible chloramphenicol resistance.

Authors:  S Horinouchi; B Weisblum
Journal:  J Bacteriol       Date:  1982-05       Impact factor: 3.490

5.  Structural and phenotypic varieties of gentamicin resistance plasmids in hospital strains of Staphylococcus aureus and coagulase-negative staphylococci.

Authors:  H W Jaffe; H M Sweeney; R A Weinstein; S A Kabins; C Nathan; S Cohen
Journal:  Antimicrob Agents Chemother       Date:  1982-05       Impact factor: 5.191

6.  Constitutive penicillinase formation in Staphylococcus aureus owing to a mutation unlinked to the penicillinase plasmid.

Authors:  S Cohen; H M Sweeney
Journal:  J Bacteriol       Date:  1968-04       Impact factor: 3.490

7.  Molecular epidemiology of multiresistant Staphylococcus aureus in Australian hospitals.

Authors:  B R Lyon; J L Iuorio; J W May; R A Skurray
Journal:  J Med Microbiol       Date:  1984-02       Impact factor: 2.472

8.  Aminocyclitol resistance in Staphylococcus aureus: presence of plasmids and aminocyclitol-modifying enzymes.

Authors:  G S Gray; R T Huang; J Davies
Journal:  Plasmid       Date:  1983-03       Impact factor: 3.466

9.  Conjugational transfer of gentamicin resistance plasmids intra- and interspecifically in Staphylococcus aureus and Staphylococcus epidermidis.

Authors:  R W McDonnell; H M Sweeney; S Cohen
Journal:  Antimicrob Agents Chemother       Date:  1983-01       Impact factor: 5.191

10.  Two restriction and modification systems in Staphylococcus aureus NCTC8325.

Authors:  S Iordanescu; M Surdeanu
Journal:  J Gen Microbiol       Date:  1976-10
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  58 in total

1.  Identification of aminoglycoside-modifying enzymes by susceptibility testing: epidemiology of methicillin-resistant Staphylococcus aureus in Japan.

Authors:  T Ida; R Okamoto; C Shimauchi; T Okubo; A Kuga; M Inoue
Journal:  J Clin Microbiol       Date:  2001-09       Impact factor: 5.948

2.  Diversity of Tn4001 transposition products: the flanking IS256 elements can form tandem dimers and IS circles.

Authors:  M Prudhomme; C Turlan; J-P Claverys; M Chandler
Journal:  J Bacteriol       Date:  2002-01       Impact factor: 3.490

3.  Disruption of gene mg218 of Mycoplasma genitalium through homologous recombination leads to an adherence-deficient phenotype.

Authors:  S Dhandayuthapani; W G Rasmussen; J B Baseman
Journal:  Proc Natl Acad Sci U S A       Date:  1999-04-27       Impact factor: 11.205

4.  Transposase-dependent formation of circular IS256 derivatives in Staphylococcus epidermidis and Staphylococcus aureus.

Authors:  Isabel Loessner; Katja Dietrich; Dorothea Dittrich; Jörg Hacker; Wilma Ziebuhr
Journal:  J Bacteriol       Date:  2002-09       Impact factor: 3.490

5.  A single gene on the staphylococcal multiresistance plasmid pSK1 encodes a novel partitioning system.

Authors:  Alice E Simpson; Ronald A Skurray; Neville Firth
Journal:  J Bacteriol       Date:  2003-04       Impact factor: 3.490

6.  Insertions of IS256-like element flanking the chromosomal beta-lactamase gene of Enterococcus faecalis CX19.

Authors:  L B Rice; S H Marshall
Journal:  Antimicrob Agents Chemother       Date:  1994-04       Impact factor: 5.191

7.  Molecular characterization of the staphylococcal multidrug resistance export protein QacC.

Authors:  I T Paulsen; M H Brown; S J Dunstan; R A Skurray
Journal:  J Bacteriol       Date:  1995-05       Impact factor: 3.490

Review 8.  The Enterococcus: a Model of Adaptability to Its Environment.

Authors:  Mónica García-Solache; Louis B Rice
Journal:  Clin Microbiol Rev       Date:  2019-01-30       Impact factor: 26.132

9.  Diversity of structures carrying the high-level gentamicin resistance gene (aac6-aph2) in Enterococcus faecalis strains isolated in France.

Authors:  A Casetta; A B Hoï; G de Cespédès; T Horaud
Journal:  Antimicrob Agents Chemother       Date:  1998-11       Impact factor: 5.191

10.  Characterization of IS1272, an insertion sequence-like element from Staphylococcus haemolyticus.

Authors:  G L Archer; J A Thanassi; D M Niemeyer; M J Pucci
Journal:  Antimicrob Agents Chemother       Date:  1996-04       Impact factor: 5.191
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