Literature DB >> 6322932

Localization of thyrotropin-releasing hormone (TRH) receptors in the septal nucleus of the rat brain.

S M Simasko, A Horita.   

Abstract

[3H](3MeHis2)TRH binding was examined in the septal nucleus of rats given brain lesions which destroyed specific neuronal elements within the septum. Kainic acid injected directly into the septum caused a 35% decrease in receptor binding. All other lesions did not significantly alter receptor binding. These data suggest that the septal TRH receptors are located on kainic acid-sensitive cell bodies.

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Year:  1984        PMID: 6322932     DOI: 10.1016/0006-8993(84)90081-7

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  5 in total

1.  Dual modulation of K+ currents and cytosolic Ca2+ by the peptide TRH and its derivatives in guinea-pig septal neurones.

Authors:  J Toledo-Aral; A Castellano; J Ureña; J López-Barneo
Journal:  J Physiol       Date:  1993-12       Impact factor: 5.182

2.  Thyrotropin-releasing-hormone (TRH) and its physiological metabolite TRH-OH inhibit Na+ channel activity in mammalian septal neurons.

Authors:  J López-Barneo; A Castellano; J Toledo-Aral
Journal:  Proc Natl Acad Sci U S A       Date:  1990-10       Impact factor: 11.205

3.  Effect of a thyrotrophin-releasing hormone analogue, RX77368, on AMPA-induced septal-hippocampal lesioned rats in an operant delayed non-matching to position test.

Authors:  T M Ballard; A J Hunter; G W Bennett
Journal:  Psychopharmacology (Berl)       Date:  1996-10       Impact factor: 4.530

4.  Down-regulation of thyrotropin-releasing hormone (TRH) receptors in spinal cord after transection as revealed by quantitative autoradiography.

Authors:  G Vita; C K Haun; E F Hawkins; W K Engel
Journal:  Exp Brain Res       Date:  1991       Impact factor: 1.972

5.  Effect of injection of thyrotropin-releasing hormone into nucleus accumbens on pain discharges in nucleus parafascicularis of the thalamus in rats.

Authors:  Z G Nie; Z Y Liu
Journal:  J Tongji Med Univ       Date:  1991
  5 in total

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