Literature DB >> 6322758

Segmental homologies in the coding and 3' non-coding sequences of rat liver cytochrome P-450e and P-450b cDNAs and cytochrome P-450e-like genes.

M Affolter, A Anderson.   

Abstract

The nucleotide sequence of a cloned cDNA insert carried by pHDQ14 was determined and found to code for the 107 C-terminal amino acids of rat liver cytochrome P-450e. Comparison of the pHQ14 cDNA sequence with those of cloned cDNAs for cytochrome P-450b and of 2 P-450e-like genes revealed segmental homologies that may have resulted from gene conversion. These results suggest that gene conversion may generate sequence variants of genes for rat liver cytochrome P-450s.

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Year:  1984        PMID： 6322758     DOI： 10.1016/0006-291x(84)91353-6

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  3 in total

1.  Gene conversion in a cytochrome P-450 gene family.

Authors:  M Atchison; M Adesnik
Journal:  Proc Natl Acad Sci U S A       Date:  1986-04       Impact factor: 11.205

2.  Rat alpha 1-fetoprotein messenger RNA: 5'-end sequence and glucocorticoid-suppressed liver transcription in an improved nuclear run-off assay.

Authors:  B Turcotte; M Guertin; M Chevrette; L Bélanger
Journal:  Nucleic Acids Res       Date:  1985-04-11       Impact factor: 16.971

3.  Polymorphisms of four hepatic cytochromes P-450 in twenty-eight inbred strains of rat.

Authors:  A Rampersaud; F G Walz
Journal:  Biochem Genet       Date:  1987-08       Impact factor: 1.890
  3 in total

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