Literature DB >> 6321996

Alteration of c-myc chromatin structure by avian leukosis virus integration.

W Schubach, M Groudine.   

Abstract

The most common sites of integration of the leukosis virus (ALV) long terminal repeat (LTR) in bursal lymphomas and derivative cell lines correspond to a region encompassed by two major hypersensitive sites in the 5' flanking region of the pre-integration, unrearranged c-myc gene. After integration of the ALV LTR, the major hypersensitive site within the avian c-myc oncogene region is within the proviral LTR, and the major hypersensitive sites normally found in uninfected cells 5' to the first c-myc coding exon are no longer detectable.

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Year:  1984        PMID： 6321996     DOI： 10.1038/307702a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  33 in total

1.  Transcriptionally active genome regions are preferred targets for retrovirus integration.

Authors:  U Scherdin; K Rhodes; M Breindl
Journal:  J Virol       Date:  1990-02       Impact factor: 5.103

2.  Multiple single-stranded cis elements are associated with activated chromatin of the human c-myc gene in vivo.

Authors:  G A Michelotti; E F Michelotti; A Pullner; R C Duncan; D Eick; D Levens
Journal:  Mol Cell Biol       Date:  1996-06       Impact factor: 4.272

Review 3.  Provirus tagging as an instrument to identify oncogenes and to establish synergism between oncogenes.

Authors:  A Berns
Journal:  Arch Virol       Date:  1988       Impact factor: 2.574

4.  Transcriptional regulation of the human cytomegalovirus major immediate-early gene is associated with induction of DNase I-hypersensitive sites.

Authors:  J A Nelson; M Groudine
Journal:  Mol Cell Biol       Date:  1986-02       Impact factor: 4.272

5.  Alternate structures and stabilities of c-myc RNA in a bursal lymphoma cell line.

Authors:  W H Schubach; G Horvath
Journal:  Nucleic Acids Res       Date:  1988-12-09       Impact factor: 16.971

6.  Interference of the simian virus 40 origin of replication by the cytomegalovirus immediate early gene enhancer: evidence for competition of active regulatory chromatin conformation in a single domain.

Authors:  P H Chen; W B Tseng; Y Chu; M T Hsu
Journal:  Mol Cell Biol       Date:  2000-06       Impact factor: 4.272

7.  Ongoing diversification of the rearranged immunoglobulin light-chain gene in a bursal lymphoma cell line.

Authors:  S Kim; E H Humphries; L Tjoelker; L Carlson; C B Thompson
Journal:  Mol Cell Biol       Date:  1990-06       Impact factor: 4.272

8.  Rapid and reversible changes in nucleosome structure accompany the activation, repression, and superinduction of murine fibroblast protooncogenes c-fos and c-myc.

Authors:  T A Chen; V G Allfrey
Journal:  Proc Natl Acad Sci U S A       Date:  1987-08       Impact factor: 11.205

9.  Differential selection of cells with proviral c-myc and c-erbB integrations after avian leukosis virus infection.

Authors:  M Gong; H L Semus; K J Bird; B J Stramer; A Ruddell
Journal:  J Virol       Date:  1998-07       Impact factor: 5.103

10.  Nucleotide sequence 5' of the chicken c-myc coding region: localization of a noncoding exon that is absent from myc transcripts in most avian leukosis virus-induced lymphomas.

Authors:  C K Shih; M Linial; M M Goodenow; W S Hayward
Journal:  Proc Natl Acad Sci U S A       Date:  1984-08       Impact factor: 11.205
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