Literature DB >> 6321630

The alpha-globin pseudogene on mouse chromosome 17 is closely linked to H-2.

P D'Eustachio, B Fein, J Michaelson, B A Taylor.   

Abstract

DNA sequences homologous to adult alpha-globin genes are dispersed in the mouse. Two functional genes are tightly linked on chromosome 11. Pseudogenes have been assigned to chromosomes 15 and 17 by analysis of interspecies somatic cell hybrids. We have now further characterized the second of these pseudogenes, Hba-a4. The gene is highly polymorphic, with three forms occurring in a panel of 15 inbred strains and a fourth occurring in an inbred strain derived from M. m. molossinus. Analysis of Hba-a4 alleles in CXB, BXH, and AKXL recombinant inbred strains placed Hba-a4 6.60 +/- 3.14 cM centromeric to H-2. Analysis of congenic mouse strains confirmed the linkage and the gene order. Hba-a4 is the first mammalian dispersed pseudogene to be localized in a linkage map, and should provide a useful marker for the region of chromosome 17 proximal to H-2.

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Year:  1984        PMID: 6321630      PMCID: PMC2187240          DOI: 10.1084/jem.159.3.958

Source DB:  PubMed          Journal:  J Exp Med        ISSN: 0022-1007            Impact factor:   14.307


  14 in total

1.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

2.  Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I.

Authors:  P W Rigby; M Dieckmann; C Rhodes; P Berg
Journal:  J Mol Biol       Date:  1977-06-15       Impact factor: 5.469

3.  Dispersion of alpha-like globin genes of the mouse to three different chromosomes.

Authors:  A Leder; D Swan; F Ruddle; P D'Eustachio; P Leder
Journal:  Nature       Date:  1981 Sep 17-23       Impact factor: 49.962

4.  A mouse alpha-globin-related pseudogene lacking intervening sequences.

Authors:  E F Vanin; G I Goldberg; P W Tucker; O Smithies
Journal:  Nature       Date:  1980-07-17       Impact factor: 49.962

Review 5.  H-2 haplotypes, genes, and antigens: second listing. I. Non-H-2 loci on chromosome 17.

Authors:  J Klein; F Figueroa; D Klein
Journal:  Immunogenetics       Date:  1982       Impact factor: 2.846

6.  Somatic cell genetics and gene families.

Authors:  P D'Eustachio; F H Ruddle
Journal:  Science       Date:  1983-05-27       Impact factor: 47.728

7.  Orphons: dispersed genetic elements derived from tandem repetitive genes of eucaryotes.

Authors:  G Childs; R Maxson; R H Cohn; L Kedes
Journal:  Cell       Date:  1981-03       Impact factor: 41.582

8.  Mouse alpha-globin genes and alpha-globin-like pseudogenes are not syntenic.

Authors:  R A Popp; P A Lalley; J B Whitney; W F Anderson
Journal:  Proc Natl Acad Sci U S A       Date:  1981-10       Impact factor: 11.205

9.  Mouse globin system: a functional and evolutionary analysis.

Authors:  P Leder; J N Hansen; D Konkel; A Leder; Y Nishioka; C Talkington
Journal:  Science       Date:  1980-09-19       Impact factor: 47.728

10.  5' flanking region of immunoglobulin heavy chain constant region genes displays length heterogeneity in germlines of inbred mouse strains.

Authors:  K B Marcu; J Banerji; N A Penncavage; R Lang; N Arnheim
Journal:  Cell       Date:  1980-11       Impact factor: 41.582

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  19 in total

Review 1.  Mouse chromosome 17.

Authors:  L M Silver; K Artzt; D Barlow; K Fischer-Lindahl; M F Lyon; J Klein; L Snyder
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

Review 2.  Mouse chromosome 17.

Authors:  K Artzt; D Barlow; W F Dove; K Fischer-Lindahl; J Klein; M F Lyon; L M Silver
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

3.  Limits of the distal inversion in the t complex of the house mouse: evidence from linkage disequilibria.

Authors:  E Neufeld; V Vincek; F Figueroa; J Klein
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

4.  Comparative mapping of DNA markers from the familial Alzheimer disease and Down syndrome regions of human chromosome 21 to mouse chromosomes 16 and 17.

Authors:  S V Cheng; J H Nadeau; R E Tanzi; P C Watkins; J Jagadesh; B A Taylor; J L Haines; N Sacchi; J F Gusella
Journal:  Proc Natl Acad Sci U S A       Date:  1988-08       Impact factor: 11.205

5.  Evolution of mouse chromosome 17 and the origin of inversions associated with t haplotypes.

Authors:  M F Hammer; J Schimenti; L M Silver
Journal:  Proc Natl Acad Sci U S A       Date:  1989-05       Impact factor: 11.205

6.  Genetic analysis of mutations at the fused locus in the mouse.

Authors:  R J Greenspan; M C O'Brien
Journal:  Proc Natl Acad Sci U S A       Date:  1986-06       Impact factor: 11.205

7.  Genetic analysis of a mouse t complex locus that is homologous to a kidney cDNA clone.

Authors:  E A Mann; L M Silver; R W Elliott
Journal:  Genetics       Date:  1986-11       Impact factor: 4.562

Review 8.  Maps of mouse chromosome 17: first report. Committee for Mouse Chromosome 17.

Authors: 
Journal:  Mamm Genome       Date:  1991       Impact factor: 2.957

9.  Chromosomal location of the gene encoding the neural cell adhesion molecule (N-CAM) in the mouse.

Authors:  P D'Eustachio; G C Owens; G M Edelman; B A Cunningham
Journal:  Proc Natl Acad Sci U S A       Date:  1985-11       Impact factor: 11.205

10.  Eukaryotic chromosome transfer: linkage of the murine major histocompatibility complex to an inserted dominant selectable marker.

Authors:  J H Weis; D L Nelson; M J Przyborski; D D Chaplin; R C Mulligan; D E Housman; J G Seidman
Journal:  Proc Natl Acad Sci U S A       Date:  1984-08       Impact factor: 11.205

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