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Literature DB >> 6321159

Regulation of the uvrC gene of Escherichia coli K12: localization and characterization of a damage-inducible promoter.

C A van Sluis, G F Moolenaar, C Backendorf.

Abstract

Operon fusion and S1 nuclease mapping have been employed to locate a putative uvrC promoter, which is situated approximately 200 bp ahead of the uvrC structural gene. The promoter sustains transcription towards the uvrC coding sequence and is inducible by DNA damaging agents. The inducibility is dependent on the Escherichia coli LexA and RecA functions. Examination of the DNA sequence in the promoter region reveals the presence of a sequence similar to the consensus of a SOS box. In contrast to the related uvrA and uvrB genes, uvrC gene expression is characterized by a delayed onset of induction after DNA damaging treatment. Furthermore, no induction is observed with nalidixic acid.

Entities: Chemical

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Year: 1983 PMID： 6321159 PMCID： PMC555450 DOI： 10.1002/j.1460-2075.1983.tb01739.x

Source DB: PubMed Journal: EMBO J ISSN： 0261-4189 Impact factor: 11.598

36 in total

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3. Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids.

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Journal: Cell Date: 1977-11 Impact factor: 41.582

Review 4. DNA repair in bacteria and mammalian cells.

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Journal: Annu Rev Biochem Date: 1979 Impact factor: 23.643

5. A novel repair enzyme: UVRABC excision nuclease of Escherichia coli cuts a DNA strand on both sides of the damaged region.

Authors: A Sancar; W D Rupp
Journal: Cell Date: 1983-05 Impact factor: 41.582

6. In vivo regulation of the uvrA gene: role of the "-10" and "-35" promoter regions.

Authors: C Backendorf; J A Brandsma; T Kartasova; P van de Putte
Journal: Nucleic Acids Res Date: 1983-09-10 Impact factor: 16.971

7. Characterisation of the promoter for the LexA regulated sulA gene of Escherichia coli.

Authors: S T Cole
Journal: Mol Gen Genet Date: 1983

8. A mutant of Escherichia coli showing constitutive expression of the lysogenic induction and error-prone DNA repair pathways.

Authors: D W Mount
Journal: Proc Natl Acad Sci U S A Date: 1977-01 Impact factor: 11.205

9. Expression of the uvrB gene of Escherichia coli: in vitro construction of a pMB9 uvrB plasmid.

Authors: H Pannekoek; I A Noordermeer; C A van Sluis; P van de Putte
Journal: J Bacteriol Date: 1978-02 Impact factor: 3.490

10. uvrC gene function in excision repair in toluene-treated Escherichia coli.

Authors: S Sharma; R E Moses
Journal: J Bacteriol Date: 1979-01 Impact factor: 3.490

24 in total

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Review 2. Linkage map of Escherichia coli K-12, edition 10: the traditional map.

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Journal: Microbiol Mol Biol Rev Date: 1998-09 Impact factor: 11.056

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Journal: Microbiol Rev Date: 1990-06

4. Analysis of regulatory sequences upstream of the E. coli uvrB gene; involvement of the DnaA protein.

Authors: E A van den Berg; R H Geerse; J Memelink; R A Bovenberg; F A Magnée; P van de Putte
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5. Structure of the uvrB gene of Escherichia coli. Homology with other DNA repair enzymes and characterization of the uvrB5 mutation.

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Journal: Nucleic Acids Res Date: 1986-04-11 Impact factor: 16.971