Literature DB >> 6320856

Experimental herpetic keratitis in rabbit corneal organ cultures.

D H Percy, M O Creighton, L A Hatch, E De Clercq.   

Abstract

An in-vitro method for maintaining rabbit corneal organ cultures for short periods of time is described. These cultures supported replication of strains of type 1 and 2 herpes simplex virus, and changes typical of herpetic infections of the cornea in vivo were observed by light microscopy, and by scanning and transmission electron microscopy. Infectious virus was readily recovered from inoculated corneal organ cultures. For practical, economic and humanitarian reasons, the full potential of this system warrants further investigation.

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Year:  1984        PMID： 6320856      PMCID： PMC2040934     

Source DB:  PubMed          Journal:  Br J Exp Pathol        ISSN： 0007-1021


  11 in total

Review 1.  Herpetic keratitis. Proctor Lecture.

Authors:  H E Kaufman
Journal:  Invest Ophthalmol Vis Sci       Date:  1978-10       Impact factor: 4.799

2.  Experimental infection with herpes simplex virus type 2 in newborn rats: Effects of treatment with iododeoxyuridine and cytosine arabinoside.

Authors:  D H Percy; L A Hatch
Journal:  J Infect Dis       Date:  1975-09       Impact factor: 5.226

3.  Herpes simplex virus types 1 and 2 in ocular disease.

Authors:  D Neumann-Haefelin; R Sundmacher; G Wochnik; B Bablok
Journal:  Arch Ophthalmol       Date:  1978-01

Review 4.  Objectives in therapy of herpetic eye disease.

Authors:  B R Jones; M G Falcon; H P Williams; D J Coster
Journal:  Trans Ophthalmol Soc U K       Date:  1977-07

5.  Comparison of types 1 and 2 Herpesvirus hominis infection of rabbit eyes. I. Clinical manifestations.

Authors:  J O O; T R Stevens
Journal:  Arch Ophthalmol       Date:  1973-12

6.  Rapid identification and typing of herpes simplex virus types 1 and 2 by a direct immunofluorescence technique.

Authors:  A Nahmias; I DelBuono; J Pipkin; R Hutton; C Wickliffe
Journal:  Appl Microbiol       Date:  1971-09

7.  Comparison of types 1 and 2 Herpesvirus hominis infection of rabbit eyes. II. Histopathologic and virologic studies.

Authors:  T R Stevens; J O O
Journal:  Arch Ophthalmol       Date:  1973-12

8.  Lesions produced by human herpesviruses 1 and 2. Morphologic features in rabbit corneal epithelium.

Authors:  M J Hollenberg; J S Wilkie; J B Hudson; B J Lewis
Journal:  Arch Ophthalmol       Date:  1976-01

9.  Herpes simplex eye infections: clinical manifestations, pathogenesis and management.

Authors:  C R Dawson; B Togni
Journal:  Surv Ophthalmol       Date:  1976 Sep-Oct       Impact factor: 6.048

10.  Experimental type 2 herpes simplex ophthalmitis in the newborn rat.

Authors:  D H Percy; K A Galil; L A Hatch; L B Pancer; J P Crawford
Journal:  Invest Ophthalmol Vis Sci       Date:  1980-05       Impact factor: 4.799
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  1 in total

1.  Pathogenesis of Aujeszky's disease virus infection in swine tracheal organ culture.

Authors:  M Narita; T Imada; M Kobayashi
Journal:  J Comp Pathol       Date:  1991-11       Impact factor: 1.311
  1 in total

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