Literature DB >> 6320832

3T3 variants unable to bind epidermal growth factor cannot complement in co-culture.

E Terwilliger, H R Herschman.   

Abstract

A Swiss-Webster 3T3 variant, called 3T3-ENR7, unable to divide in response to epidermal growth factor was isolated by the mitogen-colchicine selection technique. Like the other EGF non-proliferative variants (3T3-NR6 and 3T3-TNR2), 3T3-ENR7 was unable to bind 125I-EGF. Pairwise co-culture of the three independently isolated EGF non-responsive variants did not restore mitogenic responsiveness to EGF.

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Year:  1984        PMID： 6320832     DOI： 10.1016/0006-291x(84)91067-2

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  2 in total

1.  Epidermal growth factor-nonresponsive 3T3 variants do not contain epidermal growth factor receptor-related antigens or mRNA.

Authors:  C A Schneider; R W Lim; E Terwilliger; H R Herschman
Journal:  Proc Natl Acad Sci U S A       Date:  1986-01       Impact factor: 11.205

2.  A 12-O-tetradecanoylphorbol-13-acetate (TPA)-nonproliferative variant of 3T3 cells is resistant to TPA-enhanced gene amplification.

Authors:  H R Herschman
Journal:  Mol Cell Biol       Date:  1985-05       Impact factor: 4.272
  2 in total

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