Literature DB >> 6320770

The characterization and purification of DNA binding proteins present within herpes simplex virus infected cells using monoclonal antibodies.

N B la Thangue, W L Chan.   

Abstract

Hybridomas secreting monoclonal antibodies against herpes simplex virus (HSV) DNA binding proteins (DBP) have been produced. Five HSV DBP have been characterized according to molecular weight, affinity for DNA, kinetic class and localization within the infected cell. By preparing an immunoadsorbent column from antibody TI8, its specific DBP was purified to apparent homogeneity. The purified DBP retained the ability to bind to DNA.

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Year:  1984        PMID: 6320770     DOI: 10.1007/bf01314300

Source DB:  PubMed          Journal:  Arch Virol        ISSN: 0304-8608            Impact factor:   2.574


  41 in total

1.  Isolation of pure IgG1, IgG2a and IgG2b immunoglobulins from mouse serum using protein A-sepharose.

Authors:  P L Ey; S J Prowse; C R Jenkin
Journal:  Immunochemistry       Date:  1978-07

2.  A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels.

Authors:  W M Bonner; R A Laskey
Journal:  Eur J Biochem       Date:  1974-07-01

3.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

4.  Purification of glycoprotein gD of herpes simplex virus types 1 and 2 by use of monoclonal antibody.

Authors:  R J Eisenberg; M Ponce de Leon; L Pereira; D Long; G H Cohen
Journal:  J Virol       Date:  1982-03       Impact factor: 5.103

5.  Herpes simplex virus non-structural proteins. III. Function of the major DNA-binding protein.

Authors:  E Littler; D Purifoy; A Minson; K L Powell
Journal:  J Gen Virol       Date:  1983-05       Impact factor: 3.891

Review 6.  lambda Repressor and cro--components of an efficient molecular switch.

Authors:  A D Johnson; A R Poteete; G Lauer; R T Sauer; G K Ackers; M Ptashne
Journal:  Nature       Date:  1981-11-19       Impact factor: 49.962

7.  Properties of herpesvirus-induced "immediate early" polypeptides.

Authors:  R T Hay; J Hay
Journal:  Virology       Date:  1980-07-15       Impact factor: 3.616

8.  A herpes simplex virus type 1 function continuously required for early and late virus RNA synthesis.

Authors:  R J Watson; J B Clements
Journal:  Nature       Date:  1980-05-29       Impact factor: 49.962

9.  Herpes simplex virus gene expression in transformed cells. I. Regulation of the viral thymidine kinase gene in transformed L cells by products of superinfecting virus.

Authors:  J M Leiden; R Buttyan; P G Spear
Journal:  J Virol       Date:  1976-11       Impact factor: 5.103

10.  Type-common and type-specific monoclonal antibody to herpes simplex virus type 1.

Authors:  L Pereira; T Klassen; J R Baringer
Journal:  Infect Immun       Date:  1980-08       Impact factor: 3.441

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  3 in total

1.  Interactions between herpes simplex virus and murine bone marrow macrophages.

Authors:  S Howie; M Norval; J Maingay; W H McBride
Journal:  Arch Virol       Date:  1986       Impact factor: 2.574

2.  A cultured human oligodendroglioma cell line and herpes simplex virus-infected cells share antigenic determinants.

Authors:  P G Kennedy; B A Watkins; N B LaThangue; G B Clements; D G Thomas
Journal:  J Neurooncol       Date:  1987       Impact factor: 4.130

3.  Helper T cells induced by an immunopurified herpes simplex virus type I (HSV-I) 115 kilodalton glycoprotein (gB) protect mice against HSV-I infection.

Authors:  W L Chan; M L Lukig; F Y Liew
Journal:  J Exp Med       Date:  1985-10-01       Impact factor: 14.307

  3 in total

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