Literature DB >> 6320749

Effect of catecholestrogens on prostaglandin release by rat pituitaries superfused in vitro.

U Gethmann, J M Grognet, F Dray.   

Abstract

We studied the action of catecholestrogens on prostaglandin and LH release by female rat pituitaries superfused in vitro. Their actions were compared to those of estradiol (E2) at the same concentration (10(-6) M). By comparison with E2 the action of 2-OHE2 was only the same on total PGE2 release. 4-OHE2-17 beta stimulated LH like E2 but the values for PGD2 and PGE2 were about 20-30% lower. However, the release of 6-keto-PGF1 alpha was about 35% higher. 4-OHE2-17 alpha had no comparable action on PG release but stimulated a significant LH release. There was no action on TxB2 in any case.

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Year:  1983        PMID： 6320749     DOI： 10.1007/bf00207685

Source DB:  PubMed          Journal:  Arch Gynecol        ISSN： 0170-9925


  6 in total

1.  The effect of various prostaglandins and a prostaglandin synthetase inhibitor on rat anterior pituitary cyclic AMP levels and hormone release in vitro (38475).

Authors:  D K Sundberg; C P Fawcett; P Illner; S M McCann
Journal:  Proc Soc Exp Biol Med       Date:  1975-01

Review 2.  Roles for the prostaglandins in the regulation of anterior pituitary secretion.

Authors:  G A Hedge
Journal:  Life Sci       Date:  1977-01-01       Impact factor: 5.037

3.  Prostaglandin-induced release of pituitary gonadotropins: central nervous system and pituitary sites of action.

Authors:  P G Harms; S R Ojeda; S M McCann
Journal:  Endocrinology       Date:  1974-05       Impact factor: 4.736

Review 4.  Catecholoestrogens (2-and 4-hydroxyoestrogens): chemistry, biogenesis, metabolism, occurrence and physiological significance.

Authors:  P Ball; R Knuppen
Journal:  Acta Endocrinol Suppl (Copenh)       Date:  1980

5.  New approach to the RIA of prostaglandins and related compounds using iodinated tracers.

Authors:  F Dray; K Gerozissis; B Kouznetzova; S Mamas; P Pradelles; G Trugnan
Journal:  Adv Prostaglandin Thromboxane Res       Date:  1980

6.  Catechol oestrogens stimulate and direct prostaglandin synthesis.

Authors:  R W Kelly; M H Abel
Journal:  Prostaglandins       Date:  1980-10
  6 in total

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