Literature DB >> 6320374

T-cell growth factor gene: lack of expression in human T-cell leukemia-lymphoma virus-infected cells.

S K Arya, F Wong-Staal, R C Gallo.   

Abstract

Activated mature T cells require T-cell growth factor (TCGF) for continuous proliferation. However, many mature T cells infected with human T-cell leukemia-lymphoma virus grow independently of exogenously added TCGF. It is now reported that cells infected with this virus also lack detectable TCGF messenger RNA (less than one copy per cell) and thus do not produce their own growth factor. The results apparently rule out an autostimulation mechanism of growth control.

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Year:  1984        PMID： 6320374     DOI： 10.1126/science.6320374

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  38 in total

1.  Autocrine/paracrine cytokine stimulation of leukemic cell proliferation in smoldering and chronic adult T-cell leukemia.

Authors:  Jing Chen; Mike Petrus; Bonita R Bryant; Vinh Phuc Nguyen; Carolyn K Goldman; Richard Bamford; John C Morris; John E Janik; Thomas A Waldmann
Journal:  Blood       Date:  2010-09-21       Impact factor: 22.113

2.  Temporal regulation of viral and cellular gene expression during human T-lymphotropic virus type I-mediated lymphocyte immortalization.

Authors:  J T Kimata; L Ratner
Journal:  J Virol       Date:  1991-08       Impact factor: 5.103

3.  Stable expression of the tax gene of type I human T-cell leukemia virus in human T cells activates specific cellular genes involved in growth.

Authors:  Y Wano; M Feinberg; J B Hosking; H Bogerd; W C Greene
Journal:  Proc Natl Acad Sci U S A       Date:  1988-12       Impact factor: 11.205

4.  Aberrant activation of the interleukin-2 autocrine loop through the nuclear factor of activated T cells by nonleukemogenic human T-cell leukemia virus type 2 but not by leukemogenic type 1 virus.

Authors:  Akiko Niinuma; Masaya Higuchi; Masahiko Takahashi; Masayasu Oie; Yuetsu Tanaka; Fumitake Gejyo; Nobuyuki Tanaka; Kazuo Sugamura; Li Xie; Patrick L Green; Masahiro Fujii
Journal:  J Virol       Date:  2005-09       Impact factor: 5.103

Review 5.  Mechanisms of T-cell activation by human T-cell lymphotropic virus type I.

Authors:  P Höllsberg
Journal:  Microbiol Mol Biol Rev       Date:  1999-06       Impact factor: 11.056

6.  Transcriptional regulation of a tumor promoter and mitogen-inducible gene in human lymphocytes.

Authors:  S K Arya; F Wong-Staal; R C Gallo
Journal:  Mol Cell Biol       Date:  1984-11       Impact factor: 4.272

7.  The human T-cell leukemia/lymphotropic virus type 1 p12I proteins bind the interleukin-2 receptor beta and gammac chains and affects their expression on the cell surface.

Authors:  J C Mulloy; R W Crownley; J Fullen; W J Leonard; G Franchini
Journal:  J Virol       Date:  1996-06       Impact factor: 5.103

8.  Molecular cloning of gene sequences regulated by tumor promoters and mitogens through protein kinase C.

Authors:  M D Johnson; G M Housey; P T Kirschmeier; I B Weinstein
Journal:  Mol Cell Biol       Date:  1987-08       Impact factor: 4.272

9.  Theileria parva infection induces autocrine growth of bovine lymphocytes.

Authors:  D A Dobbelaere; T M Coquerelle; I J Roditi; M Eichhorn; R O Williams
Journal:  Proc Natl Acad Sci U S A       Date:  1988-07       Impact factor: 11.205

Review 10.  Distinct functions of HTLV-1 Tax1 from HTLV-2 Tax2 contribute key roles to viral pathogenesis.

Authors:  Masaya Higuchi; Masahiro Fujii
Journal:  Retrovirology       Date:  2009-12-17       Impact factor: 4.602
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