| Literature DB >> 6320017 |
Abstract
The protein oligomer forming the gap junction channel has been analysed in two Ca2+-sensitive states by electron microscopy of membranes in frozen aqueous solutions. Switching between states occurs by a small cooperative rearrangement involving tilting of the subunits, which may be responsible for the effect of Ca2+ on channel permeability in vivo.Entities:
Mesh:
Substances:
Year: 1984 PMID: 6320017 DOI: 10.1038/307609a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962