Literature DB >> 6319079

A practical computer-based approach to the analysis of radioligand binding experiments.

G A McPherson.   

Abstract

EBDA is a computer program designed to process raw data (dpm) obtained from radioligand binding experiments into a form suitable for use by a non-linear curve fitting program. Processing of the data is facilitated by graphical representation in the form of Scatchard and Hill plots for saturation data, and competition curves and Hofstee plots for drug displacement studies. Preliminary estimates of binding constants required by a non-linear curve fitting program can also be obtained.

Mesh：

Substances：

Year:  1983        PMID： 6319079     DOI： 10.1016/0010-468x(83)90031-4

Source DB:  PubMed          Journal:  Comput Programs Biomed        ISSN： 0010-468X


  131 in total

1.  Characterization of two new ETB selective radioligands, [125I]-BQ3020 and [125I]-[Ala1,3,11,15]ET-1 in human heart.

Authors:  P Molenaar; R E Kuc; A P Davenport
Journal:  Br J Pharmacol       Date:  1992-11       Impact factor: 8.739

2.  Identification of a region of the C-terminal domain involved in short-term desensitization of the prostaglandin EP4 receptor.

Authors:  M Bastepe; B Ashby
Journal:  Br J Pharmacol       Date:  1999-01       Impact factor: 8.739

3.  The significance of functional receptor heterogeneity in the biological responses of the rabbit neutrophil to stimulation by chemotactic formyl peptides.

Authors:  J C Kermode; R J Freer; E L Becker
Journal:  Biochem J       Date:  1991-06-15       Impact factor: 3.857

4.  The interleukin-1 receptor in Raji human B-lymphoma cells. Molecular characterization and evidence for receptor-mediated activation of gene expression.

Authors:  R Horuk; J A McCubrey
Journal:  Biochem J       Date:  1989-06-15       Impact factor: 3.857

5.  Growth effects of epidermal growth factor (EGF) and a monoclonal antibody against the EGF receptor on four glioma cell lines.

Authors:  M H Werner; P A Humphrey; D D Bigner; S H Bigner
Journal:  Acta Neuropathol       Date:  1988       Impact factor: 17.088

6.  Enhancement by a single dose of reserpine (plus alpha methyl-p-tyrosine) of the central stimulatory effects evoked by dopamine D-1 and D-2 agonists in the mouse.

Authors:  S B Ross; D M Jackson; E M Wallis; S R Edwards
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1988-05       Impact factor: 3.000

7.  [3H]-rauwolscine binding to alpha 2-adrenoceptors in the mammalian kidney: apparent receptor heterogeneity between species.

Authors:  C B Neylon; R J Summers
Journal:  Br J Pharmacol       Date:  1985-06       Impact factor: 8.739

8.  The influence of molecular structure on the affinity and efficacy of some beta-adrenoceptor agonists.

Authors:  P Molenaar; G A McPherson; E Malta; C Raper
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1985-11       Impact factor: 3.000

9.  The in vitro pharmacology of xamoterol (ICI 118,587).

Authors:  E Malta; M A Mian; C Raper
Journal:  Br J Pharmacol       Date:  1985-05       Impact factor: 8.739

10.  Purification to homogeneity of an active opioid receptor from rat brain by affinity chromatography.

Authors:  S Loukas; M Mercouris; F Panetsos; C Zioudrou
Journal:  Proc Natl Acad Sci U S A       Date:  1994-05-10       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.