Literature DB >> 6318833

Vitamin C stimulates the chlorinating activity of human myeloperoxidase.

B G Bolscher, G R Zoutberg, R A Cuperus, R Wever.   

Abstract

Ascorbic acid (vitamin C) was found to stimulate the chlorinating activity of human myeloperoxidase (donor:hydrogen peroxide oxidoreductase, EC 1.11.1.7) 3-fold in vitro and to shift the pH optimum of the reaction to higher pH values. These effects are due to the conversion by ascorbic acid of inactive compound II formed during turnover into native enzyme.

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Year:  1984        PMID： 6318833     DOI： 10.1016/0167-4838(84)90127-4

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  9 in total

1.  Vitamin C protects against and reverses specific hypochlorous acid- and chloramine-dependent modifications of low-density lipoprotein.

Authors:  A C Carr; T Tijerina; B Frei
Journal:  Biochem J       Date:  2000-03-01       Impact factor: 3.857

2.  NADPH as a co-substrate for studies of the chlorinating activity of myeloperoxidase.

Authors:  F Auchère; C Capeillère-Blandin
Journal:  Biochem J       Date:  1999-11-01       Impact factor: 3.857

3.  Superoxide modulates the activity of myeloperoxidase and optimizes the production of hypochlorous acid.

Authors:  A J Kettle; C C Winterbourn
Journal:  Biochem J       Date:  1988-06-01       Impact factor: 3.857

4.  Cyanate-mediated inhibition of neutrophil myeloperoxidase activity.

Authors:  M Qian; J W Eaton; S P Wolff
Journal:  Biochem J       Date:  1997-08-15       Impact factor: 3.857

5.  Influence of superoxide on myeloperoxidase kinetics measured with a hydrogen peroxide electrode.

Authors:  A J Kettle; C C Winterbourn
Journal:  Biochem J       Date:  1989-11-01       Impact factor: 3.857

6.  Analysis of the mechanism by which melatonin inhibits human eosinophil peroxidase.

Authors:  T Lu; S Galijasevic; I Abdulhamid; H M Abu-Soud
Journal:  Br J Pharmacol       Date:  2008-06-02       Impact factor: 8.739

7.  Disruption of heme-peptide covalent cross-linking in mammalian peroxidases by hypochlorous acid.

Authors:  Husam M Abu-Soud; Dhiman Maitra; Faten Shaeib; Sana N Khan; Jaeman Byun; Ibrahim Abdulhamid; Zhe Yang; Ghassan M Saed; Michael P Diamond; Peter R Andreana; Subramaniam Pennathur
Journal:  J Inorg Biochem       Date:  2014-07-08       Impact factor: 4.155

8.  Myeloperoxidase scavenges peroxynitrite: A novel anti-inflammatory action of the heme enzyme.

Authors:  Chintan N Koyani; Joerg Flemmig; Ernst Malle; Juergen Arnhold
Journal:  Arch Biochem Biophys       Date:  2015-02-27       Impact factor: 4.013

9.  Long-Term Effects of (-)-Epigallocatechin Gallate (EGCG) on Pristane-Induced Arthritis (PIA) in Female Dark Agouti Rats.

Authors:  Anna Leichsenring; Ingo Bäcker; Paul G Furtmüller; Christian Obinger; Franziska Lange; Jörg Flemmig
Journal:  PLoS One       Date:  2016-03-29       Impact factor: 3.240
  9 in total

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