Literature DB >> 6318757

Angiotensin II receptors negatively coupled to adenylate cyclase in rat aorta.

M B Anand-Srivastava.   

Abstract

Angiotensin II (AII) inhibited adenylate cyclase from rat aorta in a concentration dependent manner. The maximal inhibition (approximately 20%) was observed at 10 microM. The inhibitory effect of angiotensin II was dependent on monovalent cations such as Na+ or Li+ and was blocked by saralasin, an antagonist of angiotensin. Guanine nucleotides such as GTP or GMP-P (NH)P were also required to elicit the inhibition by angiotensin II. In addition, angiotensin II also inhibited the stimulation exerted by catecholamines. These data suggest that angiotensin receptors are present in aorta which are negatively coupled to adenylate cyclase.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6318757     DOI： 10.1016/0006-291x(83)91217-2

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  12 in total

1.  Parallel regulation of arginine transport and nitric oxide synthesis by angiotensin II in vascular smooth muscle cells role of protein kinase C.

Authors:  M Rivera-Correa; P I Altieri; N Escobales
Journal:  Amino Acids       Date:  1996-06       Impact factor: 3.520

2.  Angiotensin II inhibits rat arterial KATP channels by inhibiting steady-state protein kinase A activity and activating protein kinase Ce.

Authors:  Y Hayabuchi; N W Davies; N B Standen
Journal:  J Physiol       Date:  2001-01-15       Impact factor: 5.182

3.  Angiotensin II inhibition of ATP-sensitive K+ currents in rat arterial smooth muscle cells through protein kinase C.

Authors:  M Kubo; J M Quayle; N B Standen
Journal:  J Physiol       Date:  1997-09-15       Impact factor: 5.182

4.  Presence of renin secretory granules in rat adrenal gland and stimulation of renin secretion by angiotensin II but not by adrenocorticotropin.

Authors:  K Mizuno; L H Hoffman; J C McKenzie; T Inagami
Journal:  J Clin Invest       Date:  1988-09       Impact factor: 14.808

5.  Angiotensin II stimulates early proximal bicarbonate absorption in the rat by decreasing cyclic adenosine monophosphate.

Authors:  F Y Liu; M G Cogan
Journal:  J Clin Invest       Date:  1989-07       Impact factor: 14.808

6.  Angiotensins stimulate in vitro ovulation and contraction of brook trout (Salvelinus fontinalis) follicles.

Authors:  S Y Hsu; F W Goetz
Journal:  Fish Physiol Biochem       Date:  1992-12       Impact factor: 2.794

7.  Natriuretic peptide receptor-C activation attenuates angiotensin II-induced enhanced oxidative stress and hyperproliferation of aortic vascular smooth muscle cells.

Authors:  Padma Madiraju; Ekhtear Hossain; Madhu B Anand-Srivastava
Journal:  Mol Cell Biochem       Date:  2018-02-07       Impact factor: 3.396

8.  Enhanced expression of inhibitory guanine nucleotide regulatory protein in spontaneously hypertensive rats. Relationship to adenylate cyclase inhibition.

Authors:  M B Anand-Srivastava
Journal:  Biochem J       Date:  1992-11-15       Impact factor: 3.857

9.  Angiotensin II-activated Ca2+ entry-induced release of Ca2+ from intracellular stores in rat portal vein myocytes.

Authors:  J L Morel; N Macrez-Leprêtre; J Mironneau
Journal:  Br J Pharmacol       Date:  1996-05       Impact factor: 8.739

10.  Mutation of Asp74 of the rat angiotensin II receptor confers changes in antagonist affinities and abolishes G-protein coupling.

Authors:  C Bihoreau; C Monnot; E Davies; B Teutsch; K E Bernstein; P Corvol; E Clauser
Journal:  Proc Natl Acad Sci U S A       Date:  1993-06-01       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.