Literature DB >> 6318504

Ultrastructural study of effect of ACTH4-10 on nerve regeneration; axons become larger in number and smaller in diameter.

W A Bijlsma, E van Asselt, H Veldman, F G Jennekens, P Schotman, W H Gispen.   

Abstract

Electron-microscopic analysis of the regenerating sciatic nerve in the rat showed that ACTH4-10 treatment stimulated the number of regenerating myelinated and unmyelinated fibers to a similar degree. Fourteen days following a crush lesion of the sciatic nerve, 23% more regenerating fibers were present in the ACTH4-10-treated group of animals. The increase in number of regenerating fibers was accompanied by a comparable decrease in axon diameter. The ACTH4-10 treatment did not change the number of lamellae in the myelin sheath.

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Year:  1983        PMID: 6318504     DOI: 10.1007/bf00684916

Source DB:  PubMed          Journal:  Acta Neuropathol        ISSN: 0001-6322            Impact factor:   17.088


  15 in total

1.  Acceleration of peripheral nervous regeneration in the rat by exogenous triiodothyronine.

Authors:  S A Cockett; J A Kiernan
Journal:  Exp Neurol       Date:  1973-06       Impact factor: 5.330

2.  Biosynthesis and intra-axonal transport of proteins during neuronal regeneration.

Authors:  D Giulian; H Des Ruisseux; D Cowburn
Journal:  J Biol Chem       Date:  1980-07-10       Impact factor: 5.157

3.  Specific changes in rapidly transported proteins during regeneration of the goldfish optic nerve.

Authors:  L I Benowitz; V E Shashoua; M G Yoon
Journal:  J Neurosci       Date:  1981-03       Impact factor: 6.167

4.  ACTH accelerates recovery of neuromuscular function following crushing of peripheral nerve.

Authors:  F L Strand; T T Kung
Journal:  Peptides       Date:  1980       Impact factor: 3.750

5.  The effects of dibutyryl cyclic adenosine monophosphate on the degeneration and regeneration of crush-lesioned rat sciatic nerves.

Authors:  M R Gershenbaum; F J Roisen
Journal:  Neuroscience       Date:  1980       Impact factor: 3.590

6.  Regeneration and protein synthesis in the spinal cord: the influence of ACTH-like peptides on cell-free protein synthesis.

Authors:  W A Bijlsma; P Schotman; F G Jennekens; W H Gispen
Journal:  Neurosci Lett       Date:  1983-08-08       Impact factor: 3.046

7.  Changes in synthesis of specific proteins in axotomized dorsal root ganglia.

Authors:  M E Hall
Journal:  Exp Neurol       Date:  1982-04       Impact factor: 5.330

Review 8.  LPH, ACTH, MSH and motor systems.

Authors:  F L Strand; C M Smith
Journal:  Pharmacol Ther       Date:  1980       Impact factor: 12.310

9.  Changes in synthesis of specific proteins following axotomy: detection with two-dimensional gel electrophoresis.

Authors:  M E Hall; D L Wilson; G C Stone
Journal:  J Neurobiol       Date:  1978-09

10.  The use of lead citrate at high pH as an electron-opaque stain in electron microscopy.

Authors:  E S REYNOLDS
Journal:  J Cell Biol       Date:  1963-04       Impact factor: 10.539

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  2 in total

1.  Cloning, expression, and tissue distribution of a fifth melanocortin receptor subtype.

Authors:  Z Fathi; L G Iben; E M Parker
Journal:  Neurochem Res       Date:  1995-01       Impact factor: 3.996

2.  Characterization of MSH/ACTH-like immunoreactivity in sciatic nerves of Xenopus laevis by immunocytochemistry, western blotting and radioimmunoassay.

Authors:  J E Tingstedt; J B Nielsen; L I Larsson
Journal:  Histochemistry       Date:  1990
  2 in total

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