Literature DB >> 631849

A new variant of human erythrocyte G6PD occurring at a high frequency amongst the population of two villages in The Gambia, West Africa.

S G Welch, I A McGregor, K Williams.   

Abstract

During the course of a large survey of red cell G6PD genotypes in The Gambia, a slow electrophoretic variant with reduced enzyme activity was found to occur at a high frequency. This variant, G6PD Gambia, was found in the following genotypic combinations: males; G6PDGam, females; G6PDA+/Gam, G6PDB+/Gam, and G6PDA-/Gam. From the electrophoretic mobility and kinetic characteristics it was concluded that G6PD Gambia was a hitherto unreported variant of G6PD. The frequency of the G6PDGam gene amongst the 1109 individuals examined was 0.024.

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Year:  1978        PMID： 631849     DOI： 10.1007/bf00272191

Source DB:  PubMed          Journal:  Hum Genet        ISSN： 0340-6717            Impact factor:   4.132


  11 in total

1.  Genetically determined electrophoretic variations of human phosphogluconate dehydrogenase.

Authors:  N D Carter; R A Fildes; L I Fitch; C W Parr
Journal:  Acta Genet Stat Med       Date:  1968

2.  Electrophoretic characterisation of glucose-6-phosphate dehydrogenase in Ghana.

Authors:  S K Owusu; A Opare-Mante
Journal:  Lancet       Date:  1972-07-01       Impact factor: 79.321

3.  [Phenotypes of erythrocytic glucose-6-phosphate dehydrogenase in black people. Examination of 301 black people living in France and description of 9 different variants. High incidence of deficiency of an enzyme of "B" mobility].

Authors:  A Kahn; P Boivin; J Lagneau
Journal:  Humangenetik       Date:  1973-05-25

4.  Human glucose-6-phosphate dehydrogenase variants: a supplementary tabulation.

Authors:  E Beutler; A Yoshida
Journal:  Ann Hum Genet       Date:  1973-10       Impact factor: 1.670

5.  Haemoglobin and glucose-6-phosphate dehydrogenase variants: distribution in relation to malaria endemicity in a Togolese population.

Authors:  U Bienzle; V C Okoye; H Gögler
Journal:  Z Tropenmed Parasitol       Date:  1972-03

Review 6.  Standardization of procedures for the study of glucose-6-phosphate dehydrogenase. Report of a WHO Scientific Group.

Authors: 
Journal:  World Health Organ Tech Rep Ser       Date:  1967

7.  Inherited quantitative variations of human phosphogluconate dehydrogenase.

Authors:  C W Parr; L I Fitch
Journal:  Ann Hum Genet       Date:  1967-05       Impact factor: 1.670

8.  Gd(minus)Matam, an African glucose-6-phosphate dehydrogenase variant with enzyme deficiency. Biochemical and immunological properties in various hemopoietic tissues.

Authors:  A Kahn; J Hakim; D Cottreau; P Boivin
Journal:  Clin Chim Acta       Date:  1975-03-10       Impact factor: 3.786

9.  Enzymic properties of different types of human erythrocyte glucose-6-phosphate dehydrogenase, with characterization of two new genetic variants.

Authors:  L Luzzatto; A Afolayan
Journal:  J Clin Invest       Date:  1968-08       Impact factor: 14.808

10.  Genetic variants of human erythrocyte glucose 6-phosphate dehydrogenase: new variants in West Africa characterized by column chromatography.

Authors:  E A Usanga; U Bienzle; R Cancedda; F A Fasuan; O Ajayi; L Luzzatto
Journal:  Ann Hum Genet       Date:  1977-01       Impact factor: 1.670
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  3 in total

1.  Serum protein polymorphisms in a village community from the Gambia, West Africa (Hp, Tf, and Gc).

Authors:  S G Welch; C A Swindlehurst; I A McGregor; K Williams
Journal:  Hum Genet       Date:  1979-04-17       Impact factor: 4.132

2.  Isoelectric focusing of human red cell phosphoglucomutase: the distribution of variant phenotypes in a village population from the Gambia, West Africa.

Authors:  S G Welch; C A Swindlehurst; I A McGregor; K Williams
Journal:  Hum Genet       Date:  1978-09-19       Impact factor: 4.132

3.  Red cell glucose 6 phosphate dehydrogenase genotypes of the population of two West African villages.

Authors:  S G Welch; J Lee; I A McGregor; K Williams
Journal:  Hum Genet       Date:  1978-09-19       Impact factor: 4.132
  3 in total

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