Literature DB >> 6318273

Studies on the mechanism of leukotriene induced coronary artery constriction.

D M Roth, A M Lefer.   

Abstract

Leukotriene (LT) C4, D4, and E4 at concentrations of 10 to 100 ng/ml were found to be potent coronary artery constrictors in the perfused cat coronary artery and perfused rat heart. In contrast, LTB4, was essentially inactive. The coronary constrictor effect of leukotrienes was not related to thromboxane release, but rather appeared to be due to a calcium mediated activation of specific leukotriene receptors.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6318273     DOI： 10.1016/0090-6980(83)90195-8

Source DB:  PubMed          Journal:  Prostaglandins        ISSN： 0090-6980


  11 in total

1.  SK&F S-106203 inhibits leukotriene C4, leukotriene D4 and leukotriene E4 vasopressor responses in the conscious rat.

Authors:  E F Smith; M J Slivjak; J W Egan; R D Eckardt; J F Newton
Journal:  Br J Pharmacol       Date:  1990-06       Impact factor: 8.739

2.  Vasoactive effects of eicosapentaenoic acid on isolated vascular smooth muscle.

Authors:  A Yanagisawa; A M Lefer
Journal:  Basic Res Cardiol       Date:  1987 Mar-Apr       Impact factor: 17.165

3.  Vascular responses to leukotriene B4, C4 and D4 following FPL 55712, indomethacin, saralasin, phentolamine and verapamil in the conscious rat.

Authors:  J Filep; E Földes-Filep; J C Frölich
Journal:  Br J Pharmacol       Date:  1987-02       Impact factor: 8.739

4.  Involvement of thromboxane and leukotriene in arachidonate induced coronary constriction in diabetic rats.

Authors:  Y Takiguchi; K Umemura; H Hashimoto; M Nakashima
Journal:  Diabetologia       Date:  1989-06       Impact factor: 10.122

5.  Formation of sulphidopeptide-leukotrienes by cell-cell interaction causes coronary vasoconstriction in isolated, cell-perfused heart of rabbit.

Authors:  A Sala; G Rossoni; C Buccellati; F Berti; G Folco; J Maclouf
Journal:  Br J Pharmacol       Date:  1993-11       Impact factor: 8.739

6.  Potentiation of leukotriene formation in pulmonary and vascular tissue.

Authors:  A M Lefer; D M Roth; D J Lefer; J B Smith
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1984-06       Impact factor: 3.000

7.  Effects of leukotrienes C4 and D4 on human isolated saphenous veins.

Authors:  S P Allen; A H Chester; P J Piper; A P Sampson; E S Akl; M H Yacoub
Journal:  Br J Clin Pharmacol       Date:  1992-11       Impact factor: 4.335

Review 8.  [Eicosanoids and phospholipases].

Authors:  M Goerig; A J Habenicht; G Schettler
Journal:  Klin Wochenschr       Date:  1985-04-01

9.  Contraction of guinea pig inferior vena cava by eicosanoids.

Authors:  L E Rinkema; C R Roman; E L VanAlstyne; S M Spaethe; J H Fleisch
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1993-11       Impact factor: 3.000

Review 10.  Cardiovascular effects of leukotrienes.

Authors:  J Fauler; J C Frölich
Journal:  Cardiovasc Drugs Ther       Date:  1989-08       Impact factor: 3.727
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.