Literature DB >> 6317143

Effect of the serotonin reuptake inhibitor fluoxetine on corticotropin-releasing factor and vasopressin secretion into hypophysial portal blood.

D M Gibbs, W Vale.   

Abstract

The relative role of corticotropin-releasing factor (CRF) and arginine vasopressin (AVP) in mediating serotonin-induced ACTH secretion was studied using the serotonin reuptake inhibitor fluoxetine. Fluoxetine caused a significant increase in ACTH and AVP concentrations in peripheral plasma as well as a significant increase in CRF and AVP concentrations in hypophysial portal plasma. The data suggest that increased secretion of ACTH induced by fluoxetine is mediated, at least in part, by an increase in the hypothalamic secretion of both CRF and AVP.

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Year:  1983        PMID： 6317143     DOI： 10.1016/0006-8993(83)91189-7

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  26 in total

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2.  Brain serotonin metabolism during water deprivation and hydration in rats.

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3.  Corticotropin releasing factor (CRF): studies in alcohol preferring and non-preferring rats.

Authors:  C L Ehlers; R I Chaplin; T L Wall; L Lumeng; T K Li; M J Owens; C B Nemeroff
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Review 4.  Central neuroregulation of hypothalamic corticotropin-releasing hormone (CRH-41) secretion.

Authors:  S Tsagarakis; A Grossman
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5.  The effects of oral sumatriptan, a 5-HT1 receptor agonist, on circulating ACTH and cortisol concentrations in man.

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Review 8.  Role of interleukin-1 in stress responses. A putative neurotransmitter.

Authors:  F Shintani; T Nakaki; S Kanba; R Kato; M Asai
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10.  The effect of serotonergic system on nociceptin/orphanin FQ induced food intake in chicken.

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Journal:  J Physiol Sci       Date:  2013-04-25       Impact factor: 2.781
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