Literature DB >> 6316871

Induced underglycosylation of PLC/PRF/5 human hepatoma cells. Brief report.

M Clementi, P Bagnarelli, P Pauri, M Brugia.   

Abstract

The production of HBsAg and human plasma proteins by PLC/PRF/5 human hepatoma cell line was studied in the presence of glycosylation inhibitors. The data presented here suggest that HBsAg release in culture medium by these cells is not reduced by an inhibition of glycosylation and that Tunicamycin may play a role in a mobilization of the intracellular pool of antigen.

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Year:  1983        PMID： 6316871     DOI： 10.1007/bf01310864

Source DB:  PubMed          Journal:  Arch Virol        ISSN： 0304-8608            Impact factor:   2.574


  17 in total

1.  Hepatitis B surface antigen produced by a human hepatoma cell line.

Authors:  J Skelly; J A Copeland; C R Howard; A J Zuckerman
Journal:  Nature       Date:  1979-12-06       Impact factor: 49.962

2.  Herpes simplex virus structural proteins.

Authors:  U Olshevsky; Y Becker
Journal:  Virology       Date:  1970-04       Impact factor: 3.616

3.  Effect of steroids and adenine-arabinoside (araA) on growth and HBsAg production of a human hepatoma cell line.

Authors:  M Clementi; P Bagnarelli; P Pauri
Journal:  Arch Virol       Date:  1983       Impact factor: 2.574

4.  A study of the antiviral mechanism of action of 2-deoxy-D-glucose: normally glycosylated proteins are not strictly required for herpes simplex virus attachment but increase viral penetration and infectivity.

Authors:  J G Spivack; W H Prusoff; T R Tritton
Journal:  Virology       Date:  1982-11       Impact factor: 3.616

5.  Effects of glucosamine, 2-deoxyglucose, and tunicamycin on glycosylation, sulfation, and assembly of influenza viral proteins.

Authors:  K Nakamura; R W Compans
Journal:  Virology       Date:  1978-02       Impact factor: 3.616

6.  Isolation and characterization of the major protein and glycoprotein of hepatitis B surface antigen.

Authors:  D L Peterson
Journal:  J Biol Chem       Date:  1981-07-10       Impact factor: 5.157

7.  Role of carbohydrates in protein secretion and turnover: effects of tunicamycin on the major cell surface glycoprotein of chick embryo fibroblasts.

Authors:  K Olden; R M Pratt; K M Yamada
Journal:  Cell       Date:  1978-03       Impact factor: 41.582

8.  Tunicamycin inhibits glycosylation and multiplication of Sindbis and vesicular stomatitis viruses.

Authors:  R Leavitt; S Schlesinger; S Kornfeld
Journal:  J Virol       Date:  1977-01       Impact factor: 5.103

9.  Viral protein synthesis in mouse hepatitis virus strain A59-infected cells: effect of tunicamycin.

Authors:  P J Rottier; M C Horzinek; B A van der Zeijst
Journal:  J Virol       Date:  1981-11       Impact factor: 5.103

10.  Membrane characteristics of adult rat liver parenchymal cells in primary monolayer culture.

Authors:  A L Tarentino; J Galivan
Journal:  In Vitro       Date:  1980-10
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  1 in total

1.  Insulin reduces HBsAg production by PLC/PRF/5 human hepatoma cell line. Brief report.

Authors:  M Clementi; I Testa; P Bagnarelli; A Festa; P Pauri; M Brugia; L Calegari; C de Martinis
Journal:  Arch Virol       Date:  1984       Impact factor: 2.574
  1 in total

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