Literature DB >> 6316677

Penetration of cefotaxime into the pancreas.

P G Lankisch, N Klesel, K Seeger, G Seidel, K Winckler.   

Abstract

After intravenous injection of cefotaxime, higher pancreatic concentrations of the antibiotic were found in rats with experimental pancreatitis than in control animals. Also in human pancreatic pseudocysts, high and persistent concentrations of cefotaxime were found following intravenous injection. The results justify the use of cefotaxime in acute pancreatitis, whenever an antibiotic is indicated.

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Year:  1983        PMID： 6316677

Source DB:  PubMed          Journal:  Z Gastroenterol        ISSN： 0044-2771            Impact factor:   2.000


  4 in total

1.  Influence of changes in pancreatic tissue morphology and capillary blood flow on antibiotic tissue concentrations in the pancreas during the progression of acute pancreatitis.

Authors:  T Foitzik; H G Hotz; M Kinzig; F Sörgel; H J Buhr
Journal:  Gut       Date:  1997-04       Impact factor: 23.059

Review 2.  Acute and chronic pancreatitis. An update on management.

Authors:  P G Lankisch
Journal:  Drugs       Date:  1984-12       Impact factor: 9.546

3.  Effects of Chai-Qin-Cheng-Qi Decoction on cefotaxime in rats with acute necrotizing pancreatitis.

Authors:  Li-Hui Deng; Da-Kai Xiang; Ping Xue; Hai-Yan Zhang; Lei Huang; Qing Xia
Journal:  World J Gastroenterol       Date:  2009-09-21       Impact factor: 5.742

4.  The penetration of antibiotics into human pancreas.

Authors:  M Büchler; P Malfertheiner; H Friess; R Bittner; E Vanek; P Schlegel; H G Beger
Journal:  Infection       Date:  1989 Jan-Feb       Impact factor: 3.553
  4 in total

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