Literature DB >> 6316503

Effect of prior immunization on induction of cervial cancer in mice by herpes simplex virus type 2.

W B Wentz, A D Heggie, D D Anthony, J W Reagan.   

Abstract

Previous studies at this laboratory showed that repeated application of inactivated herpes simplex virus type 2 to the mouse cevix produced premalignant and malignant lesions. In the present study mice were inoculated with inactivated herpes simplex virus type 2 or control solution and Freund's adjuvant by intraperitoneal and subcuaneous routes before exposure of the cervix to inactivated virus. It appears that immunization with inactivated virus conferred a protection against the induction of cervical carcinoma.

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Year:  1983        PMID： 6316503     DOI： 10.1126/science.6316503

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  6 in total

1.  Follow-up report on 50 subjects vaccinated against herpes genitalis with Skinner vaccine.

Authors:  G R Skinner; C G Fink; M Cowan; A Buchan; A Fuller; C E Hartley; J Durham; C Wiblin; J Melling
Journal:  Med Microbiol Immunol       Date:  1987       Impact factor: 3.402

Review 2.  The roles of viruses in brain tumor initiation and oncomodulation.

Authors:  Alexander Kofman; Lucasz Marcinkiewicz; Evan Dupart; Anton Lyshchev; Boris Martynov; Anatolii Ryndin; Elena Kotelevskaya; Jay Brown; David Schiff; Roger Abounader
Journal:  J Neurooncol       Date:  2011-07-01       Impact factor: 4.130

Review 3.  Cervical cancer: is herpes simplex virus type II a cofactor?

Authors:  C Jones
Journal:  Clin Microbiol Rev       Date:  1995-10       Impact factor: 26.132

4.  Induction of cervical neoplasia in the mouse by herpes simplex virus type 2 DNA.

Authors:  D D Anthony; W B Wentz; J W Reagan; A D Heggie
Journal:  Proc Natl Acad Sci U S A       Date:  1989-06       Impact factor: 11.205

5.  Immunity in the female genital tract after intravaginal vaccination of mice with an attenuated strain of herpes simplex virus type 2.

Authors:  M R McDermott; J R Smiley; P Leslie; J Brais; H E Rudzroga; J Bienenstock
Journal:  J Virol       Date:  1984-09       Impact factor: 5.103

6.  Cellular proteins expressed in herpes simplex virus transformed cells also accumulate on herpes simplex virus infection.

Authors:  J C Macnab; A Orr; N B La Thangue
Journal:  EMBO J       Date:  1985-12-01       Impact factor: 11.598
  6 in total

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