Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Absence of decremental response in decentralized muscles of a myasthenic patient.

Literature DB >> 6315636

Absence of decremental response in decentralized muscles of a myasthenic patient.

F Fiacchino, P Crenna, A Sghirlanzoni, D Peluchetti, A Allegranza.

Abstract

Decentralized muscles of patients with upper motoneurone lesions may show anomalous responses to drugs acting on acetylcholine receptors. We compared the effects produced by repetitive nerve stimulation on normal and decentralized muscles of a patient with myasthenia gravis admitted to our Institute for a right hemiparesis. A myasthenic response was observed on the left (unaffected) deltoid muscle and a normal response on the opposite (paretic) side. It is suggested that decentralization might alter the functional properties of junctional receptors.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1983 PMID： 6315636 DOI： 10.1007/bf02043492

Source DB: PubMed Journal: Ital J Neurol Sci ISSN： 0392-0461

9 in total

1. Effects of motor inactivation on the chemical sensitivity of skeletal muscle.

Authors: T R JOHNS; S THESLEFF
Journal: Acta Physiol Scand Date: 1961 Feb-Mar

2. Study of sensitivity to curare in certain neurological disorders using a regional technique.

Authors: J C Brown; J E Charlton
Journal: J Neurol Neurosurg Psychiatry Date: 1975-01 Impact factor: 10.154

3. Alterations in reactivity to acetylcholine in myasthenia gravis and carcinomatous myopathy.

Authors: D Grob; T Namba; D S Feldman
Journal: Ann N Y Acad Sci Date: 1966-01-26 Impact factor: 5.691

4. An electrophysiological study of the effects of D-tubocurarine, atropine, and alpha-bungarotoxin on the cholinergic receptor in innervated and chronically denervated mammalian skeletal muscles.

Authors: A J Lapa; E X Albuquerque; J Daly
Journal: Exp Neurol Date: 1974-05 Impact factor: 5.330

1 in total

1. Abnormal responses to succinylcholine and pancuronium in a patient with hemiparesis.

Authors: F Fiacchino; C Ariano; M Gemma; D Cerrato
Journal: Ital J Neurol Sci Date: 1990-10

1 in total

Absence of decremental response in decentralized muscles of a myasthenic patient.

1. Effects of motor inactivation on the chemical sensitivity of skeletal muscle.

2. Study of sensitivity to curare in certain neurological disorders using a regional technique.

3. Alterations in reactivity to acetylcholine in myasthenia gravis and carcinomatous myopathy.

4. An electrophysiological study of the effects of D-tubocurarine, atropine, and alpha-bungarotoxin on the cholinergic receptor in innervated and chronically denervated mammalian skeletal muscles.

5. Lifetime and conductance of acetylcholine-activated channels in normal and denervated toad sartorius muscle.

Review 6. Immunology of acetylcholine receptors in relation to myasthenia gravis.

7. Monitoring neuromuscular block may be unreliable in patients with upper-motor-neuron lesions.

8. Effect of spinal cord transection on neuromuscular function in the rat.

9. Increased activation effects of succinylcholine in neurological patients.

1. Abnormal responses to succinylcholine and pancuronium in a patient with hemiparesis.