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Literature DB >> 6315425

Comparative synergistic activity of ceftriaxone-piperacillin versus ceftriaxone-netilmicin.

Abstract

The effect of combination of ceftriaxone with piperacillin or netilmicin was studied in a total of 119 clinical isolates using the checkerboard titration technique. The isolates included Pseudomonas aeruginosa, Staphylococcus aureus, enterococci and various Enterobacteriaceae. Synergy was observed in all Streptococcus faecalis strains with both combinations. Whereas the ceftriaxone/netilmicin combination showed a higher rate of synergy against Pseudomonas aeruginosa, the rate of synergy against Enterobacteriaceae was the same for the two combinations. In no instance was antagonism encountered.

Entities: Chemical Species

Mesh：

Substances：

Year: 1983 PMID： 6315425 DOI： 10.1007/bf02013915

Source DB: PubMed Journal: Eur J Clin Microbiol ISSN： 0722-2211 Impact factor: 3.267

14 in total

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Authors: G P Bodey; B Le Blanc
Journal: Antimicrob Agents Chemother Date: 1978-07 Impact factor: 5.191

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Authors: J Klastersky; F Meunier-Carpentier; J M Prevost
Journal: Am J Med Sci Date: 1977 Mar-Apr Impact factor: 2.378

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Journal: Antimicrob Agents Chemother Date: 1981-03 Impact factor: 5.191

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Authors: P Angehrn; P J Probst; R Reiner; R L Then
Journal: Antimicrob Agents Chemother Date: 1980-12 Impact factor: 5.191

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Authors: E T Anderson; L S Young; W L Hewitt
Journal: Chemotherapy Date: 1978 Impact factor: 2.544

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Authors: H C Neu; K P Fu
Journal: Antimicrob Agents Chemother Date: 1978-05 Impact factor: 5.191

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Authors: R J Fass
Journal: Antimicrob Agents Chemother Date: 1982-06 Impact factor: 5.191

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Journal: Arzneimittelforschung Date: 1980

9. In vitro activity of ceftriaxone alone and in combination with gentamicin, tobramycin, and amikacin against Pseudomonas aeruginosa.

Authors: C Watanakunakorn
Journal: Antimicrob Agents Chemother Date: 1983-08 Impact factor: 5.191

Review 3. Ceftriaxone. A reappraisal of its antibacterial activity and pharmacokinetic properties, and an update on its therapeutic use with particular reference to once-daily administration.

Authors: R N Brogden; A Ward
Journal: Drugs Date: 1988-06 Impact factor: 9.546

Review 4. Ceftriaxone. A review of its antibacterial activity, pharmacological properties and therapeutic use.

Authors: D M Richards; R C Heel; R N Brogden; T M Speight; G S Avery
Journal: Drugs Date: 1984-06 Impact factor: 9.546

4 in total