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Literature DB >> 6313517

CO2/bicarbonate stimulates growth independently of PH in mouse mammary epithelial cells.

Abstract

Mouse mammary cells of the NMuMG line proliferated faster and formed colonies more efficiently when the air above the cells contained 5% CO2. An increase in colony forming efficiency also occurred if the bicarbonate concentration in the medium was higher (44 versus 13 mM). These growth increases induced by the CO2 or bicarbonate occurred even when the control cultures were maintained at the same pH, and they occurred at every pH tested. Both the growth rate and colony forming efficiency of the NMuMG cells were highest at pH 7.0 to 7.3.

Entities: Chemical Species

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Year: 1983 PMID： 6313517 DOI： 10.1007/bf02618096

Source DB: PubMed Journal: In Vitro ISSN： 0073-5655

25 in total

1. Carbon dioxide requirement and nucleic acid metabolism of HeLa and conjunctival cells.

Authors: R S CHANG; H LIEPINS; M MARGOLISH
Journal: Proc Soc Exp Biol Med Date: 1961-01

2. Enzymatic incorporation of carbon dioxide in oxalacetate in pigeon liver.

Authors: J B VEIGA SALLES; I HARARY; R F BANFI; S OCHOA
Journal: Nature Date: 1950-04-29 Impact factor: 49.962

3. Human epidermal cell cultures: growth and differentiation in the absence of differentiation in the absence of dermal components or medium supplements.

Authors: M Eisinger; J S Lee; J M Hefton; Z Darzynkiewicz; J W Chiao; E de Harven
Journal: Proc Natl Acad Sci U S A Date: 1979-10 Impact factor: 11.205

4. Epithelial cell cultures from normal glandular tissue of mice.

Authors: R B Owens; H S Smith; A J Hackett
Journal: J Natl Cancer Inst Date: 1974-07 Impact factor: 13.506

5. The effect of environmental pH on the growth of normal and malignant cells.

Authors: H Eagle
Journal: J Cell Physiol Date: 1973-08 Impact factor: 6.384

6. Effect of CO 2 concentration on intermediates of the Embden-Myerhof pathway and the citric acid cycle in isolated perfused rat liver.

Authors: M L McDaniel; A M Liang; W J Longmore
Journal: J Biol Chem Date: 1971-08-10 Impact factor: 5.157

CO2/bicarbonate stimulates growth independently of PH in mouse mammary epithelial cells.

1. Carbon dioxide requirement and nucleic acid metabolism of HeLa and conjunctival cells.

2. Enzymatic incorporation of carbon dioxide in oxalacetate in pigeon liver.

3. Human epidermal cell cultures: growth and differentiation in the absence of differentiation in the absence of dermal components or medium supplements.

4. Epithelial cell cultures from normal glandular tissue of mice.

5. The effect of environmental pH on the growth of normal and malignant cells.

6. Effect of CO 2 concentration on intermediates of the Embden-Myerhof pathway and the citric acid cycle in isolated perfused rat liver.

7. Regulation of renal citrate metabolism by bicarbonate ion and pH: observations in tissue slices and mitochondria.

8. The role of carbon dioxide as an essential nutrient for six permanent strains of fibroblasts.

9. pH and population density in the regulation of animal cell multiplication.

10. Responses of cells to pH changes in the medium.

1. Quantification of Low-Level Drug Effects Using Real-Time, in vitro Measurement of Oxygen Consumption Rate.

2. The bicarbonate ion is essential for efficient DNA synthesis by primary cultured rat hepatocytes.

3. BaroFuse, a novel pressure-driven, adjustable-throughput perfusion system for tissue maintenance and assessment.