Literature DB >> 6313127

Immunocytochemical localization of ACTH1-39 in the brainstem of the rat.

M A Romagnano, S A Joseph.   

Abstract

The immunocytochemical distribution of ACTH1-39 (adrenocorticotropin hormone), a member of the opiocortin family of peptides, was examined in the brainstem of the rat. Immunoreactive ACTH fibers were localized in many serotonin-containing raphe nuclei and in the norepinephrine- and dopamine-containing regions throughout the brainstem. Brainstem areas involved in pain mediation contained immunoreactive ACTH fibers as well as several cranial nerve nuclei and nuclei associated with cardiovascular and respiratory functions.

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Year:  1983        PMID: 6313127     DOI: 10.1016/0006-8993(83)90543-7

Source DB:  PubMed          Journal:  Brain Res        ISSN: 0006-8993            Impact factor:   3.252


  4 in total

1.  A dose-response analysis of the beneficial effects of the ACTH-(4-9) analogue, Org 2766, on behavioural recovery following unilateral labyrinthectomy in guinea-pig.

Authors:  D P Gilchrist; C L Darlington; P F Smith
Journal:  Br J Pharmacol       Date:  1994-01       Impact factor: 8.739

2.  Neuropeptide-Y and ACTH-immunoreactive innervation of corticotropin releasing factor (CRF)-synthesizing neurons in the hypothalamus of the rat. An immunocytochemical analysis at the light and electron microscopic levels.

Authors:  Z Liposits; L Sievers; W K Paull
Journal:  Histochemistry       Date:  1988

3.  Guinea pig medial vestibular nucleus neurons in vitro respond to ACTH4-10 at picomolar concentrations.

Authors:  C L Darlington; P F Smith; J I Hubbard
Journal:  Exp Brain Res       Date:  1990       Impact factor: 1.972

4.  Volume transmission of beta-endorphin via the cerebrospinal fluid; a review.

Authors:  Jan G Veening; Peter O Gerrits; Henk P Barendregt
Journal:  Fluids Barriers CNS       Date:  2012-08-10
  4 in total

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